The testis must create and maintain an immune privileged environment to protect maturing
germ cells from autoimmune destruction. The establishment of this protective environment is …

Sertoli cells are located in the testes where they control several key functions in
spermatogenesis. Over the past 30 years, Sertoli cells have been upgraded from a simple …

Sertoli cells (SCs) are immune privileged cells found in the testis that function to
immunologically protect maturing germ cells from immune destruction. This immune …

Duchenne muscular dystrophy (DMD) is a lethal X-linked disease affecting striated muscles,
which undergo progressive degeneration and chronic inflammation. Receptor for advanced …

Huntington's disease (HD) is a genetically heritable disorder, linked with continuing cell loss
and degeneration mostly in the striatum. Currently, cell therapy approaches in HD have …

Abstract On 19-21 November 2020, the meeting of the 30 years of the Padova Muscle Days
was virtually held while the SARS-CoV-2 epidemic was hitting the world after a seemingly …

Genetically engineered pigs play an indispensable role in the study of rare monogenic
diseases. Pigs harboring a gene responsible for a specific disease can be efficiently …

The Sertoli cells (SeCs) of the seminiferous tubules secrete a multitude of immunoregulatory
and trophic factors to provide immune protection and assist in the orderly development of …

Background Regenerative medicine and transplantation science continuously seek methods
to circumvent immune-mediated rejection and promote tissue regeneration. Sertoli cells …

Background Increased abdominal fat and chronic inflammation in the expanded adipose
tissue of obesity contribute to the development of insulin resistance and type 2 diabetes …