A lifetime of neurogenesis in the olfactory system

JH Brann, SJ Firestein - Frontiers in neuroscience, 2014 - frontiersin.org
Neurogenesis continues well beyond embryonic and early postnatal ages in three areas of
the nervous system. The subgranular zone supplies new neurons to the dentate gyrus of the …

Developing and maintaining a nose-to-brain map of odorant identity

A Dorrego-Rivas, MS Grubb - Open Biology, 2022 - royalsocietypublishing.org
Olfactory sensory neurons (OSNs) in the olfactory epithelium of the nose transduce chemical
odorant stimuli into electrical signals. These signals are then sent to the OSNs' target …

Social recognition in laboratory mice requires integration of behaviorally-induced somatosensory, auditory and olfactory cues

SH de la Zerda, S Netser, H Magalnik, M Briller… - …, 2022 - Elsevier
In humans, discrimination between individuals, also termed social recognition, can rely on a
single sensory modality, such as vision. By analogy, social recognition in rodents is thought …

Pcdh19 mediates olfactory sensory neuron coalescence during postnatal stages and regeneration

AP Martinez, AC Chung, S Huang, AJ Bisogni, Y Lin… - Iscience, 2023 - cell.com
The mouse olfactory system regenerates constantly throughout life. While genes critical for
the initial projection of olfactory sensory neurons (OSNs) to the olfactory bulb have been …

Cell type-and layer-specific plasticity of olfactory bulb interneurons following olfactory sensory neuron ablation

T Kunkhyen, TR Brechbill, SPR Berg, P Pothuri… - Scientific Reports, 2024 - nature.com
Lifelong neurogenesis endows the mouse olfactory system with a capacity for regeneration
that is unique in the mammalian nervous system. Throughout life, olfactory sensory neurons …

Immature olfactory sensory neurons provide behaviourally relevant sensory input to the olfactory bulb

JS Huang, T Kunkhyen, AN Rangel… - Nature …, 2022 - nature.com
Postnatal neurogenesis provides an opportunity to understand how newborn neurons
integrate into circuits to restore function. Newborn olfactory sensory neurons (OSNs) wire …

Rapid presynaptic maturation in naturally regenerating axons of the adult mouse olfactory nerve

LP Browne, A Crespo, MS Grubb - Cell reports, 2022 - cell.com
Successful neuronal regeneration requires the reestablishment of synaptic connectivity. This
process requires the reconstitution of presynaptic neurotransmitter release, which we …

Functional recovery of odor representations in regenerated sensory inputs to the olfactory bulb

MC Cheung, W Jang, JE Schwob… - Frontiers in neural …, 2014 - frontiersin.org
The olfactory system has a unique capacity for recovery from peripheral damage. After injury
to the olfactory epithelium (OE), olfactory sensory neurons (OSNs) regenerate and re …

Mapping odor valence in the brain of flies and mice

M Knaden, BS Hansson - Current Opinion in Neurobiology, 2014 - Elsevier
Highlights•Odors are important signs of threats and resources.•Odor valence is coded in the
brain.•Specific areas code valence already in olfactory bulb and antennal lobe.•Coding of …

Odour perception: A review of an intricate signalling pathway

A Tromelin - Flavour and Fragrance Journal, 2016 - Wiley Online Library
The perception of odours is the result of the complex processing of a signal, which initiates
at peripheral receptors and ends in the brain. Along this pathway, olfactory signal …