Background Despite advances in early detection and therapies, cancer is still one of the
most common causes of death worldwide. Since each tumor is unique, there is a need to …

Activated neutrophils release neutrophil extracellular traps (NETs) in response to a variety of
stimuli. NETosis is driven by protein-arginine deiminase type 4, with the release of …

Background & Aims Regulatory T-cells (Tregs) impair cancer immunosurveillance by
creating an immunosuppressive environment that fosters tumor cell survival. Our previous …

Acute lung injury (ALI) is a heterogeneous inflammatory condition associated with high
morbidity and mortality. Neutrophils play a key role in the development of different forms of …

Neutrophils dominate the early immune response in pathogen-induced acute lung injury, but
efforts to harness their responses have not led to therapeutic advancements. Neutrophil …

The contributions by blood cells to pathological venous thrombosis were only recently
appreciated. Both platelets and neutrophils are now recognized as crucial for thrombus …

Neutrophil extracellular traps (NETs), consisting of nuclear DNA with histones and
microbicidal proteins, are expelled from activated neutrophils during sepsis. NETs were …

Sepsis is the leading cause of death in critically ill patients in intensive care units. Early
recognition of sepsis and proper therapy are essential to reduce patient mortality. Moreover …

Evidence shows that neutrophils can protect the host against pathogens in multiple ways,
including the formation and release of neutrophil extracellular traps (NETs). NETs are web …

Neutrophil extracellular traps (NETs) are web-like chromatin structures produced and
liberated by neutrophils under inflammatory conditions which also promote the activation of …