Identification, evaluation, and management of children with autism spectrum disorder

SL Hyman, SE Levy, SM Myers, DZ Kuo, S Apkon… - …, 2020 - publications.aap.org
Autism spectrum disorder (ASD) is a common neurodevelopmental disorder with reported
prevalence in the United States of 1 in 59 children (approximately 1.7%). Core deficits are …

Effects of air pollution on the nervous system and its possible role in neurodevelopmental and neurodegenerative disorders

LG Costa, TB Cole, K Dao, YC Chang, J Coburn… - Pharmacology & …, 2020 - Elsevier
Recent extensive evidence indicates that air pollution, in addition to causing respiratory and
cardiovascular diseases, may also negatively affect the brain and contribute to central …

Autism spectrum disorder: neuropathology and animal models

M Varghese, N Keshav, S Jacot-Descombes… - Acta …, 2017 - Springer
Autism spectrum disorder (ASD) has a major impact on the development and social
integration of affected individuals and is the most heritable of psychiatric disorders. An …

A computational tool (H-MAGMA) for improved prediction of brain-disorder risk genes by incorporating brain chromatin interaction profiles

NYA Sey, B Hu, W Mah, H Fauni, JC McAfee… - Nature …, 2020 - nature.com
Most risk variants for brain disorders identified by genome-wide association studies reside in
the noncoding genome, which makes deciphering biological mechanisms difficult. A …

The cerebellum, sensitive periods, and autism

SSH Wang, AD Kloth, A Badura - Neuron, 2014 - cell.com
Cerebellar research has focused principally on adult motor function. However, the
cerebellum also maintains abundant connections with nonmotor brain regions throughout …

Patches of disorganization in the neocortex of children with autism

R Stoner, ML Chow, MP Boyle… - … England Journal of …, 2014 - Mass Medical Soc
Background Autism involves early brain overgrowth and dysfunction, which is most strongly
evident in the prefrontal cortex. As assessed on pathological analysis, an excess of neurons …

The ASD Living Biology: from cell proliferation to clinical phenotype

E Courchesne, T Pramparo, VH Gazestani… - Molecular …, 2019 - nature.com
Autism spectrum disorder (ASD) has captured the attention of scientists, clinicians and the
lay public because of its uncertain origins and striking and unexplained clinical …

Fundamental elements in autism: from neurogenesis and neurite growth to synaptic plasticity

J Gilbert, HY Man - Frontiers in cellular neuroscience, 2017 - frontiersin.org
Autism spectrum disorder (ASD) is a set of neurodevelopmental disorders with a high
prevalence and impact on society. ASDs are characterized by deficits in both social behavior …

Maternal lifestyle and environmental risk factors for autism spectrum disorders

K Lyall, RJ Schmidt… - International journal of …, 2014 - academic.oup.com
Background: Over the past 10 years, research into environmental risk factors for autism has
grown dramatically, bringing evidence that an array of non-genetic factors acting during the …

Neuron number and size in prefrontal cortex of children with autism

E Courchesne, PR Mouton, ME Calhoun… - Jama, 2011 - jamanetwork.com
Context Autism often involves early brain overgrowth, including the prefrontal cortex (PFC).
Although prefrontal abnormality has been theorized to underlie some autistic symptoms, the …