[HTML][HTML] Talin mechanotransduction in disease

Y Wang, H Huang, H Weng, C Jia, B Liao… - … International Journal of …, 2024 - Elsevier
Abstract Talin protein (Talin 1/2) is a mechanosensitive cytoskeleton protein. The unique
structure of the Talin plays a vital role in transmitting mechanical forces. Talin proteins …

Identification of TLN1 as a prognostic biomarker to effect cell proliferation and differentiation in acute myeloid leukemia

D Cui, X Cui, X Xu, W Zhang, Y Yu, Y Gao, C Mei… - BMC cancer, 2022 - Springer
The protein Talin1 encoded by the TLN1 gene is a focal adhesion-related protein that binds
to various cytoskeletal proteins and plays an important role in cell adhesion and movement …

TLN1: an oncogene associated with tumorigenesis and progression

S Li, A Chen, J Gui, H Zhou, L Zhu, Y Mi - Discover Oncology, 2024 - Springer
Abstract Talin-1 (TLN1), encoded by the TLN1 gene, is a focal adhesion-related protein
capable of binding various proteins in the cytoskeleton. It is also expressed at high levels in …

Talin1 induces epithelial-mesenchymal transition to facilitate endometrial cell migration and invasion in adenomyosis under the regulation of microRNA-145-5p

Y Wang, H Duan, S Wang, Y Quan, J Huang… - Reproductive …, 2021 - Springer
Adenomyosis (ADS) is a commonly encountered benign gynecological disorder. Epithelial-
mesenchymal transition (EMT) may serve a pivotal role in the pathogenesis of ADS. Talin1 …

[HTML][HTML] Bioinformatic approaches to the investigation of the atavistic genes implicated in cancer

A Louka, I Takan, A Pavlopoulou… - Frontiers in Bioscience …, 2021 - imrpress.com
Introduction: Cancer is a widespread phenomenon occurring across multicellular organisms
and represents a condition of atavism, wherein cells follow a path of reverse evolution that …

Talin1 promotes HCC progression by regulating NRG1/PI3K/AKT axis

J Liu, Y Lu, B Zheng, D Huang, J Song, B Wang… - 2023 - researchsquare.com
Hepatocellular carcinoma (HCC) is the world's third leading cause of cancer death, with
metastasis being the predominant cause of treatment failure. We aim to explore the role of …

Identification of TLN1 as a prognostic biomarker to effect cell proliferation and differentiation in Acute Myeloid Leukemia

W Zheng, D Cui, X Cui, W Zhang, Y Yu, X Gao, C Mei - 2022 - researchsquare.com
The protein Talin1 encoded by the TLN1 gene is a focal adhesion-related protein that binds
to various cytoskeletal proteins and plays an important role in cell adhesion and movement …