Pheochromocytoma and paraganglioma (PPGL) require prompt consideration and efficient
diagnosis and treatment to minimize associated morbidity and mortality. Once considered …

The members of the chromogranin–secretogranin family of peptide hormones, biogenic
amines, and neurotransmitters are enclosed within vesicles in the neuroendocrine system …

This review provides current understanding of the pathophysiology of pheochromocytoma
and the wide range of associated clinical manifestations that have led to earlier recognition …

Biomarkers have been the mainstay in the diagnosis and follow-up of patients with
neuroendocrine tumors (NETs) over the last few decades. In the beginning, secretory …

Chromogranin A (CgA) is gaining acceptance as a serum marker of neuroendocrine tumors.
Its specificity in differentiating between neuroendocrine and nonneuroendocrine tumors, its …

The chromogranins A and B: The first 25 years and future perspectives - ScienceDirect Skip to
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THE very first known successful operation for removal of a pheochromocytoma was
performed by Cesar Roux in February 1926 in Lausanne, Switzerland (1). CH Mayo …

Malignant phaeochromocytomas are rare tumours accounting for~ 10% of all
phaeochromocytomas; the prevalence of malignancy among paragangliomas is higher …

The overall sensitivity and specificity of urinary 5-HIAA in the presence of the carcinoid
syndrome is of the order of 70 and 90%, respectively [1, 2]. Midgut carcinoids are most liable …

I. Introduction C HROMOGRANIN A (CgA) is a 49 kilodalton protein that is produced
exclusively by endocrine and neuroendocrine cells (1–3). CgA was originally discovered in …