CyTOF® for the Masses

A Iyer, AAJ Hamers, AB Pillai - Frontiers in immunology, 2022 - frontiersin.org
Mass cytometry has revolutionized immunophenotyping, particularly in exploratory settings
where simultaneous breadth and depth of characterization of immune populations is needed …

Trial watch: chemotherapy-induced immunogenic cell death in immuno-oncology

I Vanmeerbeek, J Sprooten, D De Ruysscher… - …, 2020 - Taylor & Francis
The term 'immunogenic cell death'(ICD) denotes an immunologically unique type of
regulated cell death that enables, rather than suppresses, T cell-driven immune responses …

Integrin β1-enriched extracellular vesicles mediate monocyte adhesion and promote liver inflammation in murine NASH

Q Guo, K Furuta, F Lucien, LHG Sanchez, P Hirsova… - Journal of …, 2019 - Elsevier
Background & Aims Hepatic recruitment of monocyte-derived macrophages (MoMFs)
contributes to the inflammatory response in non-alcoholic steatohepatitis (NASH). However …

Immune landscape after allo-HSCT: TIGIT-and CD161-expressing CD4 T cells are associated with subsequent leukemia relapse

V Gournay, N Vallet, V Peux, K Vera… - Blood, The Journal …, 2022 - ashpublications.org
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is the most effective
treatment for selected patients with acute myeloid leukemia (AML) and relies on a “graft …

Comprehensive immune monitoring of clinical trials to advance human immunotherapy

FJ Hartmann, J Babdor, PF Gherardini, EAD Amir… - Cell reports, 2019 - cell.com
The success of immunotherapy has led to a myriad of clinical trials accompanied by efforts to
gain mechanistic insight and identify predictive signatures for personalization. However …

Thymus degeneration and regeneration

M Duah, L Li, J Shen, Q Lan, B Pan, K Xu - Frontiers in immunology, 2021 - frontiersin.org
The immune system's ability to resist the invasion of foreign pathogens and the tolerance to
self-antigens are primarily centered on the efficient functions of the various subsets of T …

B cell reconstitution and influencing factors after hematopoietic stem cell transplantation in children

NG van der Maas, D Berghuis, M van der Burg… - Frontiers in …, 2019 - frontiersin.org
B cell reconstitution after hematopoietic stem cell transplantation (HSCT) is variable and
influenced by different patient, donor, and treatment related factors. In this review we …

Immunoprofiling reveals cell subsets associated with the trajectory of cytomegalovirus reactivation post stem cell transplantation

L Stern, HM McGuire, S Avdic… - Nature …, 2022 - nature.com
Human cytomegalovirus reactivation is a major opportunistic infection after allogeneic
haematopoietic stem cell transplantation and has a complex relationship with post …

Immune reconstitution following hematopoietic stem cell transplantation using different stem cell sources

R Elfeky, A Lazareva, W Qasim… - Expert review of clinical …, 2019 - Taylor & Francis
Introduction: Adequate immune reconstitution post-HSCT is crucial for the success of
transplantation, and can be affected by both patient-and transplant-related factors. Areas …

Robust immunity to influenza vaccination in haematopoietic stem cell transplant recipients following reconstitution of humoral and adaptive immunity

W Zhang, LC Rowntree, R Muttucumaru… - Clinical & …, 2023 - Wiley Online Library
Objectives Influenza causes significant morbidity and mortality, especially in high‐risk
populations. Although current vaccination regimens are the best method to combat annual …