Skeletal muscle regeneration is a finely tuned process involving the activation of various
cellular and molecular processes. Satellite cells, the stem cells of skeletal muscle, are …

Skeletal muscles are essential for vital functions such as movement, postural support,
breathing, and thermogenesis. Muscle tissue is largely composed of long, postmitotic …

Dystrophin is expressed in differentiated myofibers, in which it is required for sarcolemmal
integrity, and loss-of-function mutations in the gene that encodes it result in Duchenne …

Muscle stem cells, or satellite cells, are required for skeletal muscle maintenance, growth,
and repair. Following satellite cell activation, several factors drive asymmetric cell division to …

Basement membranes are widely distributed extracellular matrices that coat the basal
aspect of epithelial and endothelial cells and surround muscle, fat, and Schwann cells …

Chargé, Sophie BP, and Michael A. Rudnicki. Cellular and Molecular Regulation of Muscle
Regeneration. Physiol Rev 84: 209–238, 2004; 10.1152/physrev. 00019.2003.—Under …

Satellite cells, the quintessential skeletal muscle stem cells, reside in a specialized local
environment whose anatomy changes dynamically during tissue regeneration. The plasticity …

The influence of the extracellular matrix (ECM) within the stem cell niche remains poorly
understood. We found that Syndecan-4 (Sdc4) and Frizzled-7 (Fzd7) form a coreceptor …

Glycosylation is an essential post-translational modification that underlies many biological
processes and diseases. α-dystroglycan (α-DG) is a receptor for matrix and synaptic proteins …

The extracellular matrix (ECM) is an interconnected macromolecular scaffold occupying the
space between cells. Amongst other functions, the ECM provides structural support to …