Cellular processes are mechanisms carried out at the cellular level that are aimed at
guaranteeing the stability of the organism they comprise. The investigation of cellular …

Neurodegenerative diseases (NDDs) affect more than 50 million people worldwide, posing
a significant global health challenge as well as a high socioeconomic burden. With aging …

Three-dimensional brain organoids have emerged as a valuable model system for studies of
human brain development and pathology. Here we establish a midbrain organoid culture …

Parkinson's disease (PD) is the second most common neurodegenerative disorder
worldwide and is caused by the degeneration and loss of dopamine (DA) neurons in the …

Human midbrain dopamine (DA) neurons are a heterogeneous group of cells that share a
common neurotransmitter phenotype and are in close anatomical proximity but display …

Due to its ability to recapitulate key pathological processes in vitro, midbrain organoid
technology has significantly advanced the modeling of Parkinson's disease over the last few …

ABSTRACT Each year, the European Summer School on Stem Cell Biology and
Regenerative Medicine (SCSS) attracts early-career researchers and actively practicing …

Organoid technology describes a scientific field that concentrates on the in vitro generation
of miniaturized tissue analogs capable of emulating intricate organotypic characteristics on …