Understanding the mysterious M2 macrophage through activation markers and effector mechanisms

T Rőszer - Mediators of inflammation, 2015 - Wiley Online Library
The alternatively activated or M2 macrophages are immune cells with high phenotypic
heterogeneity and are governing functions at the interface of immunity, tissue homeostasis …

Mechano-immunomodulation: mechanoresponsive changes in macrophage activity and polarization

S Adams, LM Wuescher, R Worth… - Annals of biomedical …, 2019 - Springer
In recent years, biomaterial-and scaffold-based immunomodulation strategies were
implemented in tissue regeneration efforts for manipulating macrophage polarization (aka …

Results of the 4th scientific workshop of the ECCO (I): pathophysiology of intestinal fibrosis in IBD

G Latella, G Rogler, G Bamias… - Journal of Crohn's …, 2014 - academic.oup.com
The fourth scientific workshop of the European Crohn's and Colitis Organization (ECCO)
focused on the relevance of intestinal fibrosis in the disease course of inflammatory bowel …

The role of physical exercise in inflammatory bowel disease

J Bilski, B Brzozowski, A Mazur-Bialy… - BioMed Research …, 2014 - Wiley Online Library
We reviewed and analyzed the relationship between physical exercise and inflammatory
bowel disease (IBD) which covers a group of chronic, relapsing, and remitting intestinal …

Metabolic inflammation in inflammatory bowel disease: crosstalk between adipose tissue and bowel

P Gonçalves, F Magro, F Martel - Inflammatory bowel diseases, 2015 - academic.oup.com
Epidemiological studies show that both the incidence of inflammatory bowel disease (IBD)
and the proportion of people with obesity and/or obesity-associated metabolic syndrome …

Modulating cellular responses to mechanical forces to promote wound regeneration

S Mascharak, HE desJardins-Park, MF Davitt… - Advances in Wound …, 2022 - liebertpub.com
Significance: Skin scarring poses a major biomedical burden for hundreds of millions of
patients annually. However, this burden could be mitigated by therapies that promote wound …

[HTML][HTML] Stromal and immune cells in gut fibrosis: the myofibroblast and the scarface

V Valatas, E Filidou, I Drygiannakis… - Annals of …, 2017 - ncbi.nlm.nih.gov
Post-inflammatory scarring is the end-result of excessive extracellular matrix (ECM)
accumulation and tissue architectural destruction. It represents a failure to effectively …

Exercise and self-reported limitations in patients with inflammatory bowel disease

EM DeFilippis, S Tabani, RU Warren… - Digestive diseases and …, 2016 - Springer
Background Limited evidence suggests that exercise may have beneficial, anti-inflammatory
effects in patients with inflammatory bowel disease (IBD). Aims The purpose of this study …

Role of fat and adipokines in intestinal inflammation

LI Kredel, A Batra, B Siegmund - Current Opinion in …, 2014 - journals.lww.com
Fat tissue as an active organ in health and disease has been ignored for too long. The last
few years of research provided evidence for the complex metabolic and immunological …

[HTML][HTML] Effects of gliadin consumption on the intestinal microbiota and metabolic homeostasis in mice fed a high-fat diet

L Zhang, D Andersen, HM Roager, MI Bahl… - Scientific reports, 2017 - nature.com
Dietary gluten causes severe disorders like celiac disease in gluten-intolerant humans.
However, currently understanding of its impact in tolerant individuals is limited. Our objective …