Liver fibrosis is an advanced liver disease condition, which could progress to cirrhosis and
hepatocellular carcinoma. To date, there is no direct approved antifibrotic therapy, and …

Transforming growth factor-β (TGF-β) signaling triggers diverse biological actions in
inflammatory diseases. In tissue fibrosis, it acts as a key pathogenic regulator for promoting …

Transforming growth factor-β (TGF-β) is a cytokine essential for the induction of the fibrotic
response and for the activation of the cancer stroma. Strong evidence suggests that a strong …

Hepatic stellate cells (HSCs) are a significant component of the hepatocellular carcinoma
(HCC) tumor microenvironment (TME). Activated HSCs transform into myofibroblast-like …

Liver fibrosis is a common pathologic stage of the development of liver failure. It has showed
that exosomes loaded with therapeutic circRNAs can be manufactured in bulk by exosome …

Hepatitis B virus (HBV) infection is one the leading risk factors for chronic hepatitis, liver
fibrosis, cirrhosis and hepatocellular cancer (HCC), which are a major global health …

Transparent conducting materials (TCMs) are required in many applications from solar cells
to transparent electronics. Developing high performance materials combining the …

Liver fibrosis is the common pathological basis of all chronic liver diseases, and is the
necessary stage for the progression of chronic liver disease to cirrhosis. As one of …

Liver fibrosis is a common pathological process of chronic liver diseases, including viral
hepatitis and alcoholic liver disease, and ultimately progresses to irreversible cirrhosis and …

Background and Aims The important roles of glutamate and metabotropic glutamate
receptor 5 (mGluR5) in HSCs have recently been reported in various liver diseases; …