Nirmatrelvir combined with ritonavir for preventing and treating COVID‐19

S Reis, MI Metzendorf, R Kuehn… - Cochrane Database …, 2023 - cochranelibrary.com
Background Oral nirmatrelvir/ritonavir (Paxlovid) aims to avoid severe COVID‐19 in
asymptomatic people or those with mild symptoms, thereby decreasing hospitalization and …

Paxlovid as a potential treatment for long COVID

MW McCarthy - Expert Opinion on Pharmacotherapy, 2023 - Taylor & Francis
ABSTRACT Introduction On 31 July 2023, the United States Department of Health and
Human Services announced the formation of the Office of Long COVID Research and …

[HTML][HTML] Nirmatrelvir exerts distinct antiviral potency against different human coronaviruses

J Li, Y Wang, K Solanki, R Atre, M Lavrijsen, Q Pan… - Antiviral Research, 2023 - Elsevier
Nirmatrelvir is the main component of Paxlovid, an oral antiviral drug approved for the
treatment of COVID-19 caused by SARS-COV-2 infection. Nirmatrelvir targets the main …

Multidisciplinary recommendations for the management of CAR-T recipients in the post-COVID-19 pandemic era

T Zhang, W Tian, S Wei, X Lu, J An, S He… - … Hematology & Oncology, 2023 - Springer
The outbreak of coronavirus disease 2019 (COVID-19) posed an unprecedented challenge
on public health systems. Despite the measures put in place to contain it, COVID-19 is likely …

Remdesivir or Nirmatrelvir/Ritonavir Therapy for Omicron SARS-CoV-2 Infection in Hematological Patients and Cell Therapy Recipients

JL Piñana, I Heras, TF Aiello, I García-Cadenas… - Viruses, 2023 - mdpi.com
Background: Scarce data exist that analyze the outcomes of hematological patients with
SARS-CoV-2 infection during the Omicron variant period who received treatment with …

Discovery of peptidomimetic spiropyrrolidine derivatives as novel 3CLpro inhibitors against SARS-CoV-2

SD Guma, Z Zhou, K Song, F Yang, J Suo… - European Journal of …, 2025 - Elsevier
Given the high pathogenicity and rapid mutation rates of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), it is imperative to sustain efforts in drug research and …

Comparison of azvudine, molnupiravir, and nirmatrelvir/ritonavir in adult patients with mild-to-moderate COVID-19: a retrospective cohort study

MP Chen, DX Jiang, JX Rang, HB Zhuo, ZG Zhou - Scientific Reports, 2024 - nature.com
This study aimed to explore the effectiveness and safety of azvudine, nirmatrelvir/ritonavir,
and molnupiravir in adult patients with mild-to-moderate COVID-19. This retrospective cohort …

H‐Bonded Supramolecular Crystals‐Coated Solid‐Phase Microextraction enables the Matrix Interference‐Free Detection of the COVID‐19 Antiviral Drugs

S Wang, Y Shi, J Yu, X Peng, L Tong… - Advanced Materials …, 2023 - Wiley Online Library
Since the outbreak of COVID‐19, many antiviral drugs have been used to treat infected
patients. Excessive drug concentrations may not only damage patients' organs, but also lead …

Modern directed antiviral COVID-19 therapy: results of multicenter clinical effectiveness and safety study of fixed nirmatrelvir+ ritonavir combination

LA Balykova, NM Selezneva… - Pharmacy & …, 2022 - journals.eco-vector.com
Modern directed antiviral COVID-19 therapy: results of multicenter clinical effectiveness and
safety study of fixed nirmatrelvir+ritonavir combination - Balykova - Pharmacy & Pharmacology …

[HTML][HTML] Современная направленная противовирусная терапия COVID-19: результаты многоцентрового клинического исследования эффективности и …

ЛА Балыкова, НМ Селезнева… - Фармация и …, 2022 - cyberleninka.ru
В статье представлены данные открытого двухэтапного многоцентрового
исследования по оценке эффективности и безопасности комбинированного препарата …