Distinguishing features of current COVID-19 vaccines: knowns and unknowns of antigen presentation and modes of action

FX Heinz, K Stiasny - npj Vaccines, 2021 - nature.com
COVID-19 vaccines were developed with an unprecedented pace since the beginning of the
pandemic. Several of them have reached market authorization and mass production …

COVID-19 vaccines in patients with cancer: immunogenicity, efficacy and safety

A Fendler, EGE de Vries… - Nature Reviews …, 2022 - nature.com
Patients with cancer have a higher risk of severe coronavirus disease (COVID-19) and
associated mortality than the general population. Owing to this increased risk, patients with …

Global landscape of SARS-CoV-2 genomic surveillance and data sharing

Z Chen, AS Azman, X Chen, J Zou, Y Tian, R Sun… - Nature …, 2022 - nature.com
Genomic surveillance has shaped our understanding of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) variants. We performed a global landscape analysis on SARS …

Neutralising antibody titres as predictors of protection against SARS-CoV-2 variants and the impact of boosting: a meta-analysis

D Cromer, M Steain, A Reynaldi, TE Schlub… - The Lancet …, 2022 - thelancet.com
Summary Background Several SARS-CoV-2 variants of concern have been identified that
partly escape serum neutralisation elicited by current vaccines. Studies have also shown …

Impact of the Delta variant on vaccine efficacy and response strategies

L Bian, Q Gao, F Gao, Q Wang, Q He, X Wu… - Expert review of …, 2021 - Taylor & Francis
ABSTRACT Introduction The Delta variant of SARS-CoV-2 has caused a new wave of the
COVID-19 epidemic in many countries. It is the most infectious variant of SARS-CoV-2 to …

Adaptive immunity and neutralizing antibodies against SARS-CoV-2 variants of concern following vaccination in patients with cancer: the CAPTURE study

A Fendler, STC Shepherd, L Au, KA Wilkinson, M Wu… - Nature cancer, 2021 - nature.com
Abstract Coronavirus disease 2019 (COVID-19) antiviral response in a pan-tumor immune
monitoring (CAPTURE)(NCT03226886) is a prospective cohort study of COVID-19 immunity …

The hyper-transmissible SARS-CoV-2 Omicron variant exhibits significant antigenic change, vaccine escape and a switch in cell entry mechanism

BJ Willett, J Grove, OA MacLean, C Wilkie, N Logan… - MedRxiv, 2022 - medrxiv.org
Vaccination-based exposure to spike protein derived from early SARS-CoV-2 sequences is
the key public health strategy against COVID-19. Successive waves of SARS-CoV-2 …

SARS-CoV-2 S2–targeted vaccination elicits broadly neutralizing antibodies

KW Ng, N Faulkner, K Finsterbusch, M Wu… - Science translational …, 2022 - science.org
Several variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have
emerged during the current coronavirus disease 2019 (COVID-19) pandemic. Although …

[PDF][PDF] The SARS-CoV-2 Lambda variant exhibits enhanced infectivity and immune resistance

I Kimura, Y Kosugi, J Wu, J Zahradnik, D Yamasoba… - Cell reports, 2022 - cell.com
Summary SARS-CoV-2 Lambda, a variant of interest, has spread in some South American
countries; however, its virological features and evolutionary traits remain unclear. In this …

Increased resistance of SARS-CoV-2 Omicron variant to neutralization by vaccine-elicited and therapeutic antibodies

T Tada, H Zhou, BM Dcosta, MI Samanovic… - …, 2022 - thelancet.com
Background SARS-CoV-2 vaccines currently authorized for emergency use have been
highly successful in preventing infection and lessening disease severity. The vaccines …