This contemporary, international, evidence-informed guidance aims to achieve the greatest
good for the greatest number of people with familial hypercholesterolaemia (FH) across …

Familial hypercholesterolaemia (FH) is a common autosomal semi-dominant and highly
penetrant disorder of the low-density lipoprotein (LDL) receptor pathway, characterised by …

BACKGROUND: Homozygous familial hypercholesterolemia (HoFH) is a rare genetic
disorder characterized by severely elevated low-density lipoprotein cholesterol (LDL-C) …

Abstract Aims Homozygous familial hypercholesterolaemia (HoFH) is a rare disorder
characterized by markedly elevated circulating low-density lipoprotein cholesterol (LDL-C) …

Lipid disorders play a critical role in the intricate development of atherosclerosis and its
clinical consequences, such as coronary heart disease and stroke. These disorders are …

One of the objectives of the Spanish Society of Arteriosclerosis is to contribute to the
knowledge, prevention and treatment of vascular diseases, which are the leading cause of …

Abstract Purpose of Review The UK National Health Service (NHS) has recently announced
a Newborn Genomes Programme (NGP) to identify infants with treatable inherited disorders …

Summary Background Homozygous familial hypercholesterolaemia (HoFH) is a rare
inherited disorder characterised by extremely high concentrations of LDL cholesterol …

Nucleic acid-based therapies are being rapidly developed for prevention and management
of cardiovascular diseases (CVD). Remarkable advancements have been achieved in the …

Reducing low-density lipoprotein cholesterol (LDL-C) levels is crucial to the prevention of
atherosclerotic cardiovascular disease (ASCVD). However, many patients, especially those …