Reactive oxygen species (ROS) are bioproducts of cellular metabolism. There is a range of
molecules with oxidizing properties known as ROS. Despite those molecules being implied …

Aging is a dynamic, time-dependent process that is characterized by a gradual accumulation
of cell damage. Continual functional decline in the intrinsic ability of living organisms to …

Imbalances in NAD+ homeostasis have been linked to aging and various diseases.
Nicotine, a metabolite of the NAD+ metabolic pathway, has been found to possess anti …

Melatonin, the major secretory product of the pineal gland, not only regulates circadian
rhythms, mood, and sleep but also has actions in neoplastic processes which are being …

Aging attenuates the overall responsiveness of the immune system to eradicate pathogens.
The increased production of pro-inflammatory cytokines by innate immune cells under basal …

We previously reported the neuroprotective effects of icariin in rat cortical neurons. Here, we
present a study on icariin's anti-aging effect in 24-month aged mice by treating them with a …

Melatonin and vitamin D are associated with the immune system and have important
functions as antioxidants. Numerous attempts have been made to identify up to date …

Cancer survivors undergone treatment face an increased risk of developing atherosclerotic
cardiovascular disease (CVD), yet the underlying mechanisms remain elusive. Recent …

Endothelial cells, which are highly dynamic cells essential to the vascular network, play an
indispensable role in maintaining the normal function of the body. Several lines of evidence …

Aging is a complex biological process characterized by the gradual decline of cellular
functions, increased susceptibility to diseases, and impaired stress responses. Hypoxia …