Green chemistry in the synthesis of pharmaceuticals

S Kar, H Sanderson, K Roy, E Benfenati… - Chemical …, 2021 - ACS Publications
The principles of green chemistry (GC) can be comprehensively implemented in green
synthesis of pharmaceuticals by choosing no solvents or green solvents (preferably water) …

[HTML][HTML] Towards the sustainable discovery and development of new antibiotics

M Miethke, M Pieroni, T Weber, M Brönstrup… - Nature Reviews …, 2021 - nature.com
An ever-increasing demand for novel antimicrobials to treat life-threatening infections
caused by the global spread of multidrug-resistant bacterial pathogens stands in stark …

Potential roles of medicinal plants for the treatment of viral diseases focusing on COVID‐19: A review

B Adhikari, BP Marasini, B Rayamajhee… - Phytotherapy …, 2021 - Wiley Online Library
The whole world is entangled by the coronavirus disease (COVID‐19) pandemic caused by
severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), people are dying in …

Natural products as sources of new drugs from 1981 to 2014

DJ Newman, GM Cragg - Journal of natural products, 2016 - ACS Publications
This contribution is a completely updated and expanded version of the four prior analogous
reviews that were published in this journal in 1997, 2003, 2007, and 2012. In the case of all …

Counting on natural products for drug design

T Rodrigues, D Reker, P Schneider, G Schneider - Nature chemistry, 2016 - nature.com
Natural products and their molecular frameworks have a long tradition as valuable starting
points for medicinal chemistry and drug discovery. Recently, there has been a revitalization …

Medicinal plant analysis: A historical and regional discussion of emergent complex techniques

M Fitzgerald, M Heinrich, A Booker - Frontiers in pharmacology, 2020 - frontiersin.org
The analysis of medicinal plants has had a long history, and especially with regard to
assessing a plant's quality. The first techniques were organoleptic using the physical senses …

Actinomycetes: A Never-Ending Source of Bioactive Compounds—An Overview on Antibiotics Production

D De Simeis, S Serra - Antibiotics, 2021 - mdpi.com
The discovery of penicillin by Sir Alexander Fleming in 1928 provided us with access to a
new class of compounds useful at fighting bacterial infections: antibiotics. Ever since, a …

Natural product and natural product derived drugs in clinical trials

MS Butler, AAB Robertson, MA Cooper - Natural product reports, 2014 - pubs.rsc.org
Covering: 2008–2013. Previous review: 2008, 25, 475 There are a significant number of
natural product (NP) drugs in development. We review the 100 NP and NP-derived …

Marketed marine natural products in the pharmaceutical and cosmeceutical industries: Tips for success

A Martins, H Vieira, H Gaspar, S Santos - Marine drugs, 2014 - mdpi.com
The marine environment harbors a number of macro and micro organisms that have
developed unique metabolic abilities to ensure their survival in diverse and hostile habitats …

Marine peptides: Bioactivities and applications

RCF Cheung, TB Ng, JH Wong - Marine drugs, 2015 - mdpi.com
Peptides are important bioactive natural products which are present in many marine
species. These marine peptides have high potential nutraceutical and medicinal values …