Biologically active secondary metabolites from the fungi

GF Bills, JB Gloer - Microbiology spectrum, 2016 - Am Soc Microbiol
Many Fungi have a well-developed secondary metabolism. The diversity of fungal species
and the diversification of biosynthetic gene clusters underscores a nearly limitless potential …

Enzymatic dimerization in the biosynthetic pathway of microbial natural products

J Liu, A Liu, Y Hu - Natural Product Reports, 2021 - pubs.rsc.org
Covering: up to August 2020 The dramatic increase in the identification of dimeric natural
products generated by microorganisms and plants has played a significant role in drug …

Aspergillus terreus species complex

C Lass-Flörl, AM Dietl, DP Kontoyiannis… - Clinical Microbiology …, 2021 - Am Soc Microbiol
Infections due to Aspergillus species are an acute threat to human health; members of the
Aspergillus section Fumigati are the most frequently occurring agents, but depending on the …

Recent advances in the genome mining of Aspergillus secondary metabolites (covering 2012–2018)

J Romsdahl, CCC Wang - Medchemcomm, 2019 - pubs.rsc.org
Secondary metabolites (SMs) produced by filamentous fungi possess diverse bioactivities
that make them excellent drug candidates. Whole genome sequencing has revealed that …

Aspergillus terreus as an industrial filamentous fungus for pharmaceutical biotechnology

X Huang, P Men, S Tang, X Lu - Current Opinion in Biotechnology, 2021 - Elsevier
Highlights•Aspergillus terreus is a valuable filamentous fungus with excellent synthetic
capacity for natural products.•A number of new secondary metabolites with pharmaceutical …

Appraisal of lactic acid bacteria as protective cultures

KK Varsha, KM Nampoothiri - Food Control, 2016 - Elsevier
Food industry employs various physical and chemical methods to control fungal
contamination of food products. However, many fungal strains are defiant to these …

Inducing secondary metabolite production by the soil-dwelling fungus Aspergillus terreus through bacterial co-culture

H Chen, G Daletos, MS Abdel-Aziz, D Thomy, H Dai… - Phytochemistry …, 2015 - Elsevier
The soil-dwelling fungus Aspergillus terreus was isolated from sediment collected from the
lake of Wadi EI Natrun in Egypt. Co-cultivation of A. terreus with the bacteria Bacillus subtilis …

Recent advances in genome mining of secondary metabolites in Aspergillus terreus

CJ Guo, CCC Wang - Frontiers in Microbiology, 2014 - frontiersin.org
Filamentous fungi are rich resources of secondary metabolites (SMs) with a variety of
interesting biological activities. Recent advances in genome sequencing and techniques in …

Genome mining reveals novel biosynthetic gene clusters in entomopathogenic bacteria

W Meesil, P Muangpat, S Sitthisak, T Rattanarojpong… - Scientific Reports, 2023 - nature.com
The discovery of novel bioactive compounds produced by microorganisms holds significant
potential for the development of therapeutics and agrochemicals. In this study, we conducted …

Development of versatile and efficient genetic tools for the marine-derived fungus Aspergillus terreus RA2905

G Yao, X Chen, Y Han, H Zheng, Z Wang, J Chen - Current Genetics, 2022 - Springer
Marine-derived Aspergillus terreus produces a variety of structurally novel secondary
metabolites, most of which show unique biological activities. However, the lack of efficient …