The Temozolomide–Doxorubicin paradox in Glioblastoma in vitro–in silico preclinical drug-screening

ME Oraiopoulou, E Tzamali, SE Psycharakis… - Scientific Reports, 2024 - nature.com
Adjuvant Temozolomide is considered the front-line Glioblastoma chemotherapeutic
treatment; yet not all patients respond. Latest trends in clinical trials usually refer to …

[HTML][HTML] Are we better together? Addressing a combined treatment of pitavastatin and temozolomide for brain cancer

J Basso, AM Matos, S Ghavami, A Fortuna… - European Journal of …, 2024 - Elsevier
Pitavastatin is commonly prescribed to treat hypercholesterolemia through the regulation of
cholesterol biosynthesis. Interestingly, it has also demonstrated a great potential for treating …

Plasma and cerebrospinal fluid population pharmacokinetics of vancomycin in patients with external ventricular drain

Z Chen, M Taubert, C Chen, C Dokos… - Antimicrobial Agents …, 2023 - Am Soc Microbiol
Vancomycin is a commonly used antibacterial agent in patients with primary central nervous
system (CNS) infection. This study aims to examine predictors of vancomycin penetration …