Research progress and future directions of immune checkpoint inhibitor combination therapy in advanced gastric cancer

P He, L Ma, B Xu, Y Wang, X Li… - … Advances in Medical …, 2024 - journals.sagepub.com
In recent years, with the continuous development of molecular immunology, immune
checkpoint inhibitors (ICIs) have also been widely used in the treatment of gastric cancer …

Pseudomonas aeruginosa in Cancer Therapy: Current Knowledge, Challenges and Future Perspectives

Z Pang, MD Gu, T Tang - Frontiers in Oncology, 2022 - frontiersin.org
Drug resistance, undesirable toxicity and lack of selectivity are the major challenges of
conventional cancer therapies, which cause poor clinical outcomes and high mortality in …

MicroRNA-138-5p suppresses non-small cell lung cancer cells by targeting PD-L1/PD-1 to regulate tumor microenvironment

N Song, P Li, P Song, Y Li, S Zhou, Q Su… - Frontiers in cell and …, 2020 - frontiersin.org
Non-small cell lung cancer (NSCLC) is still challenging for treatment owing to immune
tolerance and evasion. MicroRNA-138 (miR-138) not only acts as a tumor suppressor to …

Exosomal miR-92b-3p promotes chemoresistance of small cell lung cancer through the PTEN/AKT pathway

M Li, W Shan, Y Hua, F Chao, Y Cui, L Lv… - Frontiers in cell and …, 2021 - frontiersin.org
Resistance to first-line chemotherapy drugs has become an obstacle to improving the
clinical prognosis of patients with small cell lung cancer (SCLC). Exosomal microRNAs have …

Intravesical Pseudomonas aeruginosa mannose-sensitive Hemagglutinin vaccine triggers a tumor-preventing immune environment in an orthotopic mouse bladder …

B Wang, Z He, H Yu, Z Ou, J Chen, M Yang… - Cancer Immunology …, 2021 - Springer
Abstract Bacillus Calmette-Guerin (BCG) immunotherapy can prevent recurrence and
progression in selected patients with non-muscle-invasive bladder cancer (NMIBC); …

Therapeutic potential of Pseudomonas aeruginosa-mannose sensitive hemagglutinin (PA-MSHA) in cancer treatment

X Zheng, Y Fang, X Zou, X Wang, Z Li - Microbial Pathogenesis, 2023 - Elsevier
Pseudomonas aeruginosa is a Gram-negative bacteria and it has been demonstrated that
immunization with the outer membrane proteins of the microbe produces most of the …

Pseudomonas aeruginosa-mannose sensitive hemagglutinin injection treated cytokine-induced killer cells combined with chemotherapy in the treatment of …

C Zhang, Z Zhang, L Wang, J Han, F Li, C Shen… - International …, 2017 - Elsevier
Pseudomonas aeruginosa-mannose sensitive hemagglutinin (PA-MSHA) injection serves
as immunological adjuvant in clinical treatment of cancer patients. In present study, we …

[HTML][HTML] Neoadjuvant Pseudomonas aeruginosa mannose-sensitive hemagglutinin (PA-MSHA) and chemotherapy versus placebo plus chemotherapy in patients with …

Y Gong, H Zuo, Y Zhou, KD Yu, GY Liu… - Annals of …, 2023 - ncbi.nlm.nih.gov
Background According to preclinical experiments, Pseudomonas aeruginosa mannose-
sensitive hemagglutinin (PA-MSHA) exerts antiproliferative effects against breast cancer …

Trends in Anti-Tumor Effects of Pseudomonas aeruginosa Mannose-Sensitive-Hemagglutinin (PA-MSHA): An Overview of Positive and Negative Effects

D Bozic, J Živanović, K Živančević, K Baralić… - Cancers, 2024 - mdpi.com
Simple Summary Finding the best treatment for cancer remains one of the biggest scientific
challenges in the 21st century. Available cancer treatments have issues like drug resistance …

[HTML][HTML] Clinical efficacy of pseudomonas aeruginosa injection combined with endostar in the treatment of malignant pleural effusion: a randomized trial

J Cheng, X Zhao, Z Li, M Yang, Y Zhang… - American Journal of …, 2023 - ncbi.nlm.nih.gov
Objective: This study aims to investigate the therapeutic effects of combining pseudomonas
aeruginosa injection (PAI) with endostar on patients with malignant pleural effusion and …