Autosomal dominant polycystic kidney disease (ADPKD), with an estimated genetic
prevalence between 1: 400 and 1: 1,000 individuals, is the third most common cause of end …

Abstract Autosomal Dominant Polycystic Kidney Disease (ADPKD) is a systemic disorder
associated with polycystic liver disease (PLD) and other extrarenal manifestations, the most …

Mutation of the Cys1 gene underlies the renal cystic disease in the Cys1 cpk/cpk (cpk)
mouse that phenocopies human autosomal recessive polycystic kidney disease (ARPKD) …

Abstract Autosomal Dominant Polycystic Kidney Disease (ADPKD) is the most common
inherited renal disorder, characterized by renal cyst development leading to end-stage renal …

The c-Jun N-terminal kinase (JNK) signaling pathway mediates adaptation to stress signals
and has been associated with cell death, cell proliferation, and malignant transformation in …

Polycystic Kidney Disease (PKD) refers to a group of disorders, driven by the formation of
cysts in renal tubular cells and is currently one of the leading causes of end-stage renal …

Background Upregulation of cAMP-dependent and cAMP-independent PKA signaling is
thought to promote cystogenesis in polycystic kidney disease (PKD). PKA-I regulatory …

Fibrotic kidney injury from hepatocarcinogenesis seriously impacts treatment effect.
Astragaloside IV (AS-IV), an extract of Astragalus membranaceus, has several …

Mutation of the Cys1 gene underlies the renal cystic disease in the Cys1 cpk/cpk (cpk)
mouse that phenocopies human autosomal recessive polycystic kidney disease (ARPKD) …

Role of-JUN N-terminal kinases (JNK1/2) in the development of cancer of the biliary tract Page
1 UNIVERSIDAD COMPLUTENSE DE MADRID FACULTAD DE MEDICINA © Chaobo Chen …