Patients with suppressed immunity are at the highest risk for hospital-acquired infections.
Among these, invasive candidiasis is the most prevalent systemic fungal nosocomial …

Fungi are an understudied resource possessing huge potential for developing products that
can greatly improve human well-being. In the current paper, we highlight some important …

Engineered probiotics are a kind of new microorganisms produced by modifying original
probiotics through gene editing. With the continuous development of tools and technology …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern
(VOCs), harboring spike protein N-terminal domain (NTD) or receptor-binding domain (RBD) …

Fungal pathogens represent a major human threat affecting more than a billion people
worldwide. Invasive infections are on the rise, which is of considerable concern because …

Genome editing technology has progressed rapidly in recent years. Although traditional
gene-editing methods, including homologous recombination, zinc finger endonucleases …

The Candida genus encompasses a diverse group of ascomycete fungi that have captured
the attention of the scientific community, due to both their role in pathogenesis and emerging …

Fungal pathogens are emerging as an important cause of human disease, and Candida
albicans is among the most common causative agents of fungal infections. Studying this …

Candida viswanathii is a promising cell factory for producing dodecanedioic acid (DDA) and
other long chain dicarboxylic acids. However, metabolic engineering of C. viswanathii is …

For the fungal pathogen Candida albicans, genetic overexpression readily occurs via a
diversity of genomic alterations, such as aneuploidy and gain-of-function mutations, with …