Neutrophils are the frontline cells in response to microbial infections and are involved in a
range of inflammatory disorders in the body. In recent years, neutrophils have gained …

Neutrophil extracellular trap (NET) formation, first described in 2004 as a previously
unknown strategy of neutrophils to fight microbes, has attracted an increasing interest in the …

Reactive oxygen species (ROS) are a group of short-lived highly reactive molecules formed
intracellularly from molecular oxygen. ROS can alter biochemical, transcriptional, and …

Coronavirus 2019 (COVID-19) is a pandemic associated with a high risk of mortality. Human
serum albumin (HSA) is an acute phase reactant with antioxidant property; however, its …

Background The propensity of the activated neutrophils to form extracellular traps (NETs) is
demonstrated in multiple inflammatory conditions. In this study, we investigated the roles of …

The emergence of chemotherapeutic resistance, which is closely related to the oxidative
stress defense induced by the imbalance of reactive oxygen species (ROS), is one of the …

Reactive oxygen species (ROS) are derivatives of molecular oxygen (O 2) involved in
various physiological and pathological processes. In immune cells, ROS are mediators of …

Metastasis is a pivotal event that accelerates the prognosis of cancer patients towards
mortality. Therapies that aim to induce cell death in metastatic cells require a more detailed …

Neutrophils are the most abundant type of white blood cells circulating throughout the
bloodstream and are often considered the frontline defenders in innate immunity. However …

Peptidylarginine deiminases (PADs) are calcium-dependent enzymes that mediate
citrullination, an irreversible post-translational modification (PTM). PAD enzymes have …