The treatment of Cushing's disease

R Pivonello, M De Leo, A Cozzolino… - Endocrine …, 2015 - academic.oup.com
Abstract Cushing's disease (CD), or pituitary-dependent Cushing's syndrome, is a severe
endocrine disease caused by a corticotroph pituitary tumor and associated with increased …

Cushing's disease: pathobiology, diagnosis, and management

RR Lonser, L Nieman, EH Oldfield - Journal of neurosurgery, 2017 - thejns.org
Cushing's disease (CD) is the result of excess secretion of adrenocorticotropic hormone
(ACTH) by a benign monoclonal pituitary adenoma. The excessive secretion of ACTH …

Management of hormone-secreting pituitary adenomas

GU Mehta, RR Lonser - Neuro-oncology, 2017 - academic.oup.com
Pituitary adenomas are one of the most common primary central nervous system tumors and
have an estimated prevalence of 17%. Approximately half of pituitary adenomas secrete …

The biology of radiosurgery and its clinical applications for brain tumors

D Kondziolka, SM Shin, A Brunswick, I Kim… - Neuro …, 2015 - academic.oup.com
Stereotactic radiosurgery (SRS) was developed decades ago but only began to impact brain
tumor care when it was coupled with high-resolution brain imaging techniques such as …

Cushing's disease

H Nishioka, S Yamada - Journal of clinical medicine, 2019 - mdpi.com
In patients with Cushing's disease (CD), prompt diagnosis and treatment are essential for
favorable long-term outcomes, although this remains a challenging task. The differential …

Stereotactic radiosurgery for Cushing disease: results of an international, multicenter study

GU Mehta, D Ding, MR Patibandla… - The Journal of …, 2017 - academic.oup.com
Context Cushing disease (CD) due to adrenocorticotropic hormone–secreting pituitary
tumors can be a management challenge. Objective To better understand the outcomes of …

Gamma knife radiosurgery for pituitary tumors: a systematic review and meta-analysis

L Albano, M Losa, LR Barzaghi, A Niranjan, Z Siddiqui… - Cancers, 2021 - mdpi.com
Simple Summary Pituitary tumors represent approximately 10–15% of all brain neoplasms.
Gamma Knife, the most commonly used stereotactic radiosurgery technique worldwide …

[HTML][HTML] Functioning pituitary adenomas–current treatment options and emerging medical therapies

EV Varlamov, S McCartney, M Fleseriu - European Endocrinology, 2019 - ncbi.nlm.nih.gov
Pituitary adenomas are benign tumours comprising approximately 16% of all primary cranial
neoplasms. Functioning pituitary adenomas (prolactinomas, somatotroph, corticotroph …

Target delineation and optimal radiosurgical dose for pituitary tumors

G Minniti, MF Osti, M Niyazi - Radiation oncology, 2016 - Springer
Stereotactic radiosurgery (SRS) delivered as either single-fraction or multi-fraction SRS (2–5
fractions) is frequently employed in patients with residual or recurrent pituitary adenoma …

Role of radiosurgery in the treatment of Cushing's disease

M Losa, L Albano, M Bailo… - Journal of …, 2022 - Wiley Online Library
Radiotherapy is a useful adjuvant treatment for patients with Cushing's disease that is not
cured by surgery. In particular, Gamma Knife radiosurgery (GKRS) has been increasingly …