Due to the complex physiological structure, microenvironment and multiple physiological
barriers, traditional anti‐cancer drugs are severely restricted from reaching the tumour site …

The paradigm of drug delivery via particulate formulations is one of the leading ideas that
enable overcoming limitations of traditional chemotherapeutic agents. The trend toward …

Introduction Lung cancer is one of the cancer types with the highest mortality rate, exploring
a more effective treatment modality that improves therapeutic efficacy while mitigating side …

Combination therapy is a promising strategy to enhance the efficacy of cancer treatment.
Polyphenolic compounds including Ellagic acid (EA) have shown significant efficacy against …

Abstract Background Acetaminophen (Act) overdose is a known inducer of liver failure in
both children and adults. Cell annihilation ensues following acetaminophen overdose and …

The recent approvals for antibody–drug conjugates (ADCs) in multiple malignancies in the
past few years have fueled the ongoing development of this class of drug. However, the …

Improving hepatic glucose and lipid metabolisms is an important strategy to treat type 2
diabetes mellitus complicated with non-alcoholic fatty liver disease (T2DM-NAFLD). Silybin …

Cationic lipids play a pivotal role in developing novel drug delivery systems for diverse
biomedical applications, owing to the success of mRNA vaccines against COVID-19 and the …

Phospholipid‐based liposomes are among the most successful nanodrug delivery systems
in clinical use. However, these conventional liposomes present significant challenges …

Combination therapy represents a promising strategy in cancer management by reducing
chemotherapy resistance and associated side effects. Silymarin (SLM) has been extensively …