PEGylated and functionalized polylactide-based nanocapsules: An overview

MA de Oliveira, RS Araújo, VCF Mosqueira - International Journal of …, 2023 - Elsevier
Polymeric nanocapsules (NC) are versatile mixed vesicular nanocarriers, generally
containing a lipid core with a polymeric wall. They have been first developed over four …

Co-delivery of gentiopicroside and thymoquinone using electrospun m-PEG/PVP nanofibers: In-vitro and In vivo studies for antibacterial wound dressing in diabetic …

M Almukainzi, TA El-Masry, WA Negm… - International journal of …, 2022 - Elsevier
Nanofibers (NFs) provide several delivery advantages like their great flexibility and similarity
with extracellular matrix (ECM) which qualify them to be the unique model of a wound …

[HTML][HTML] Nanostructures for Delivery of Flavonoids with Antibacterial Potential against Klebsiella pneumoniae

HLRQ Macêdo, LL de Oliveira, DN de Oliveira… - Antibiotics, 2024 - mdpi.com
Flavonoids are secondary metabolites that exhibit remarkable biological activities, including
antimicrobial properties against Klebsiella pneumoniae, a pathogen responsible for several …

[HTML][HTML] Rosuvastatin and diosmetin inhibited the HSP70/TLR4/NF-κB p65/NLRP3 signaling pathways and switched macrophage to M2 phenotype in a rat model of …

HM Saad, E Elekhnawy, MA Shaldam… - Biomedicine & …, 2024 - Elsevier
Numerous efforts to manage acute kidney injury (AKI) were unsuccessful because its
pathophysiology is still poorly understood. Thus, our research hotspot was to explore the …

Green synthetized Cu-oxide nanoparticles: properties and applications for enhancing healing of wounds infected with Staphylococcus aureus

B Alotaibi, E Elekhnawy, TA El-Masry, A Saleh… - International Journal of …, 2023 - Elsevier
Treating wound infections is a challenging concern in various clinical settings in Egypt,
especially in the increasing global problem of resistance to antimicrobials. Here, we aimed …

Celecoxib-Loaded Cubosomal Nanoparticles as a Therapeutic Approach for Staphylococcus aureus In Vivo Infection

SZ Alshawwa, TA El-Masry, M Nasr, AY Kira… - Microorganisms, 2023 - mdpi.com
There is a great need for novel approaches to treating bacterial infections, due to the vast
dissemination of resistance among pathogenic bacteria. Staphylococcus aureus are …

[HTML][HTML] Antibacterial activity and wound healing potential of Cycas thouarsii R. Br n-butanol fraction in diabetic rats supported with phytochemical profiling

R Binsuwaidan, E Elekhnawy, WS Elseady… - Biomedicine & …, 2022 - Elsevier
Patients with diabetes mellitus often suffer from chronic wounds due to wound healing
impairment. Considering the increased prevalence of diabetes, this would predispose …

Anticancer drug-loaded chitosan nanoparticles for in vitro release, promoting antibacterial and anticancer activities

N Ahmad, MR Khan, S Palanisamy, S Mohandoss - Polymers, 2023 - mdpi.com
Targeted drug delivery to tumor cells may be possible using nanoparticles containing
human therapeutic drugs. The present study was carried out to develop cisplatin (CP) and 5 …

[HTML][HTML] Hesperidin nanoformulation: A potential strategy for reducing doxorubicin-induced renal damage via the sirt-1/HIF1-α/VEGF/NF-κB signaling cascade

FA Alherz, TA El-Masry, GA Oriquat, E Elekhnawy… - Pharmaceuticals, 2024 - mdpi.com
Hesperidin (Hes) functions as a strong antioxidant and anti-inflammatory to guard against
damage to the heart, liver, and kidneys. Nevertheless, due to its restricted solubility and …

Metabolic Profiling of Jasminum grandiflorum L. Flowers and Protective Role against Cisplatin-Induced Nephrotoxicity: Network Pharmacology and In Vivo Validation

MJ Alqahtani, SA Mostafa, IA Hussein, S Elhawary… - Metabolites, 2022 - mdpi.com
Cisplatin (CP) is a powerful chemotherapeutic agent; however, its therapeutic use is
restricted due to its nephrotoxicity. In this work, we profiled the phytoconstituents of …