Ehrlichia chaffeensis is an obligatory intracellular and cholesterol-dependent bacterium that
has evolved special proteins and functions to proliferate inside leukocytes and cause …

Obligate intracellular bacteria have remained those for which effective vaccines are
unavailable, mostly because protection does not solely rely on an antibody response …

The Structural Vaccinology (SV) approach is the logical evolution of Reverse Vaccinology: a
genome-based approach combined with structural biology, with the idea that protective …

Ehrlichia chaffeensis, an obligatory intracellular bacterium, causes human monocytic
ehrlichiosis, an emerging disease transmitted by the Lone Star tick, Amblyomma …

Tick-transmitted pathogens cause infectious diseases in both humans and animals. Different
types of adaptive immune mechanisms could be induced in hosts by these microorganisms …

Myalgic encephalomyelitis (ME, also called Chronic Fatigue Syndrome), a common disease
with chronic fatigability, cognitive dysfunction and myalgia of unknown etiology, often starts …

Acinetobacter baumannii is a Gram-negative bacterium that has recently been identified as
a leading nosocomial pathogen. Infections by this pathogen result in significant mortality due …

For decades, the defined antibody reactive proteins of Ehrlichia chaffeensis and E. canis
were limited to a small group with linear antibody epitopes. Recently, our laboratory has …

Obligate intracellular bacteria, such as Ehrlichia chaffeensis, perish unless they can enter
eukaryotic cells. E. chaffeensis is the etiological agent of human monocytic ehrlichiosis, an …

Vaccines elicit immune responses, provide protection against microorganisms and are
considered as one of the most successful medical interventions against infectious diseases …