Since the onset of microbiology in the late 19th century, scientists have been growing
microorganisms almost exclusively as pure cultures, resulting in a limited and biased view of …

Covering: 2009 up to August 2023 Prenyltransferases (PTs) are involved in the primary and
the secondary metabolism of plants, bacteria, and fungi, and they are key enzymes in the …

B otrytis cinerea is the causal agent of gray mold disease in various plant species and
produces grayish macroconidia and/or black sclerotia at the end of the infection cycle. It has …

Aromatic prenyltransferases (aPTases) transfer prenyl moieties from isoprenoid donors to
various aromatic acceptors, some of which have the rare property of extreme enzymatic …

Fungi are a prolific source of bioactive compounds, some of which have been developed as
essential medicines and life-enhancing drugs. Genome sequencing has revealed that fungi …

Infections due to Aspergillus species are an acute threat to human health; members of the
Aspergillus section Fumigati are the most frequently occurring agents, but depending on the …

Melanins are ubiquitous pigments found in all kingdoms of life. Most organisms use them for
protection from environmental stress, although some fungi employ melanins as virulence …

High throughput genome sequencing has revealed a multitude of potential secondary
metabolites biosynthetic pathways that remain cryptic. Pathway reconstruction coupled with …

Highlights•Aspergillus terreus is a valuable filamentous fungus with excellent synthetic
capacity for natural products.•A number of new secondary metabolites with pharmaceutical …

The attainment of spatiotemporally inhomogeneous chemical and physical properties within
a system is gaining attention across disciplines due to the resemblance to environmental …