Cancer phototherapy by CO releasing terpyridine-based Re (i) tricarbonyl complexes via ROS generation and NADH oxidation

R Kushwaha, A Upadhyay, S Saha, AK Yadav… - Dalton …, 2024 - pubs.rsc.org
Here, we have synthesized and characterized three visible light responsive terpyridine
based-Re (I)-tricarbonyl complexes;[Re (CO) 3 (ph-tpy) Cl](Retp1),[Re (CO) 3 (an-tpy) …

Biotin–Pt (IV)–Ru (II)–Boron–Dipyrromethene Prodrug as “Platin Bullet” for Targeted Chemo-and Photodynamic Therapy

A Bera, A Nepalia, A Upadhyay, DK Saini… - Inorganic …, 2024 - ACS Publications
Using the principle of “Magic Bullet”, a cisplatin-derived platinum (IV) prodrug
heterobimetallic Pt (IV)–Ru (II) complex, cis, cis, trans-[Pt (NH3) 2Cl2 {Ru (tpy–BODIPY)(tpy …

Multi-functional biotinylated platinum (iv)–SAHA conjugate for tumor-targeted chemotherapy

A Gupta, PK Sasmal - Dalton Transactions, 2024 - pubs.rsc.org
The development of multi-functional Pt (IV) complexes as chemotherapeutic agents has
gained growing attention in medical oncology. However, the design of multi-functional tumor …

Mechanisms of myocardial toxicity of antitumor drugs and potential therapeutic strategies: A review of the literature

Y Jia, Q Wu, Z Yang, R Sun, K Zhang, X Guo… - Current Problems in …, 2024 - Elsevier
With the successive development of chemotherapy drugs, good results have been achieved
in clinical application. However, myocardial toxicity is the biggest challenge. Anthracyclines …

Green Light-Triggered Photocatalytic Anticancer Activity of Terpyridine-Based Ru (II) Photocatalysts

AA Mandal, V Singh, S Saha, S Peters… - Inorganic …, 2024 - ACS Publications
The relentless increase in drug resistance of platinum-based chemotherapeutics has
opened the scope for other new cancer therapies with novel mechanisms of action (MoA) …

Visible and Red Light-Triggered Anticancer Profile of a Ferrocene-Re (I)-Tricarbonyl Conjugate: Experimental and Theoretical Studies

R Kushwaha, A Upadhyay, S Peters, AK Yadav… - Langmuir, 2024 - ACS Publications
We have red-shifted the light absorbance property of a Re (I)-tricarbonyl complex via distant
conjugation of a ferrocene moiety and developed a novel complex ReFctp,[Re (Fctp)(CO) …

Nanoformulation of the Photoactive Cisplatin Prodrug for Combined Photothermal Therapy and Bioimaging

DV Spector, V Bykusov, A Zharova… - ACS Applied Nano …, 2024 - ACS Publications
Cancer phototheranostics is a new mode of precise treatment based on fluorescent and
photothermal imaging (PTI), combined with photodynamic (PDT) and photothermal therapy …

Light-Responsive Pt (IV) Prodrugs with Controlled Photoactivation and Low Dark Toxicity

D Spector, A Bubley, A Zharova, V Bykusov… - ACS Applied Bio …, 2024 - ACS Publications
Light-induced release of cisplatin from Pt (IV) prodrugs represents a promising approach for
precise control over the antiproliferative activity of Pt-based chemotherapeutic drugs. This …

Sm (Ⅲ), Gd (Ⅲ), and Eu (Ⅲ) complexes with 8‐hydroxyquinoline derivatives as potential anticancer agents via inhibiting cell proliferation, blocking cell cycle, and …

K Yang, HQ Li, MQ Hu, MX Ma, YQ Gu… - Drug Development …, 2024 - Wiley Online Library
Four lanthanide complexes with 8‐hydroxyquinoline‐2‐aldehyde‐2‐hydrazinopyridine (H‐
L1), 8‐hydroxyquinoline‐2‐aldehyde‐2‐hydrazimidazole (H‐L2):[Sm (L1) 2][Sm (L1)(NO3) …

Green Light Activated Dual‐Action Pt (IV) Prodrug With Enhanced PDT activity

OO Krasnovskaya, D Spector, V Bykusov… - …, 2024 - Wiley Online Library
Light induced release of cisplatin from Pt (IV) prodrugs is a promising tool for precise
spatiotemporal control over the antiproliferative activity of Pt‐based chemotherapeutic drugs …