Diabetes mellitus has been associated with an increased risk of several types of cancers,
but its relationship with breast cancer remains unclear. We conducted a meta‐analysis of …

Body mass index, as an approximation of body adiposity, is associated with increased risk of
several common and less common malignancies in a sex-and site-specific manner. These …

BACKGROUND: Insulin-like growth factor 1 (IGF1) stimulates mitosis and inhibits apoptosis.
Some published results have shown an association between circulating IGF1 and breast …

Accumulating epidemiological evidence shows that being either overweight or obese, in
other words having excess body weight (EBW), is associated with an increased risk of …

Excess body weight (overweight and obesity) is characterized by chronic hyperinsulinaemia
and insulin resistance, and is implicated both in cancer risk and cancer mortality. The list of …

Abstract CD4+ CD25+ regulatory T cells (Treg), an essential subset for preventing
autoimmune diseases, is implicated as a negative regulator in anti-tumor immunity. We …

Numerous epidemiological and pre-clinical studies have demonstrated that the
insulin/insulin-like growth factor (IGF) system plays a key role in the development and …

BACKGROUND Greater body mass index (BMI), a measure of overall adiposity, is
associated with a higher risk of postmenopausal breast cancer. The role of central adiposity …

Significant correlations between obesity and incidence of various cancers have been
reported. Obesity, considered a mild inflammatory process, is characterized by a high level …

Obesity is an independent risk factor for breast cancer, and obese breast cancer patients
exhibit a higher risk for larger tumor burden and increased metastasis. Obesity, as …