Recently, it was proposed that there is a common mechanism behind the activity of
bactericidal antibiotics, involving the production of reactive oxygen species (ROS). However …

The high rates of morbidity and mortality caused by fungal infections are associated with the
current limited antifungal arsenal and the high toxicity of the compounds. Additionally …

Antimicrobial peptides (AMPs) are essential elements of thehost defense system.
Characterized by heterogenous structures and broad‐spectrumaction, they are promising …

During the development of antimicrobial peptides (AMP) as potential therapeutics,
antimicrobial susceptibility testing (AST) stands as an essential part of the process in …

Most antifungal peptides (AFPs), if not all, have membrane activity, while some also have
alternative targets. Fungal membranes share many characteristics with mammalian …

Candida albicans, one of the pathogenic Candida species, causes high mortality rate in
immunocompromised and high-risk surgical patients. In the last decade, only one new class …

Cyclic β-sheet decapeptides from the tyrocidine group and the homologous gramicidin S
were the first commercially used antibiotics, yet it remains unclear exactly how they kill …

Unlike superficial fungal infections of the skin and nails, which are the most common fungal
diseases in humans, invasive fungal infections carry high morbidity and mortality …

The high incidence and mortality of invasive fungal infections and serious drug resistance
have become a global public health issue. The ability of fungal cells to form biofilms is an …

Candida albicans is a major cause of human infections, ranging from relatively simple to
treat skin and mucosal diseases to systemic life-threatening invasive candidiasis. Fungal …