Revisiting the dose constraints for head and neck OARs in the current era of IMRT

NP Brodin, WA Tomé - Oral oncology, 2018 - Elsevier
Head and neck cancer poses a particular challenge in radiation therapy, whilst being an
effective treatment modality it requires very high doses of radiation to provide effective …

Generalizability assessment of head and neck cancer NTCP models based on the TRIPOD criteria

M Sharabiani, E Clementel, N Andratschke… - Radiotherapy and …, 2020 - Elsevier
This review aimed to provide an overview of the level of maturity of normal tissue
complication probability (NTCP) models for head and neck cancer (HNC) patients. A …

Volumetric modulated arc therapy of head-and-neck cancer on a fast-rotating O-ring linac: Plan quality and delivery time comparison with a C-arm linac

S Michiels, K Poels, W Crijns, L Delombaerde… - Radiotherapy and …, 2018 - Elsevier
Background and purpose Linac improvements in gantry speed, leaf speed and dose rate
may increase the time-efficiency of volumetric modulated arc therapy (VMAT) delivery. The …

De-escalated adjuvant therapy after transoral robotic surgery for human papillomavirus-related oropharyngeal carcinoma: The Sinai robotic surgery (SIRS) trial

BA Miles, MR Posner, V Gupta, MS Teng… - The …, 2021 - academic.oup.com
Background Treatment of human papillomavirus-related oropharyngeal squamous cell
carcinoma (HPVOPC) results in unprecedented high survival rates but possibly unnecessary …

Comprehensive viral genotyping reveals prognostic viral phylogenetic groups in HPV16-associated squamous cell carcinoma of the oropharynx

TP Schrank, L Landess, WH Stepp, H Rehmani… - Molecular Cancer …, 2022 - AACR
Abstract Human papillomavirus–positive (HPV+) squamous cell carcinoma of the
oropharynx (OPSCC) is the most prevalent HPV-associated malignancy in the United States …

Education in radiation oncology—current challenges and difficulties

CC Mireștean, RI Iancu, DPT Iancu - International Journal of …, 2022 - mdpi.com
The evolution and development of radiotherapy in the last two decades has meant that
postgraduate medical training has not kept up with this rapid progress both in terms of …

Genomic heterogeneity and copy number variant burden are associated with poor recurrence‐free survival and 11q loss in human papillomavirus‐positive squamous …

TP Schrank, N Lenze, LP Landess, A Hoyle, J Parker… - Cancer, 2021 - Wiley Online Library
Background Human papillomavirus–positive (HPV+) squamous cell carcinoma of the
oropharynx (OPSCC) is the most prevalent HPV‐associated malignancy in the United …

Human papillomavirus-related non-metastatic oropharyngeal carcinoma: current local treatment options and future perspectives

M Svajdova, P Dubinsky, T Kazda, B Jeremic - Cancers, 2022 - mdpi.com
Simple Summary Current options for the curative treatment of the non-metastatic
oropharyngeal carcinoma associated with human papillomavirus include minimally-invasive …

Fitting NTCP models to bladder doses and acute urinary symptoms during post-prostatectomy radiotherapy

P Mavroidis, KA Pearlstein, J Dooley, J Sun… - Radiation …, 2018 - Springer
Background To estimate the radiobiological parameters of three popular normal tissue
complication probability (NTCP) models, which describe the dose-response relations of …

[HTML][HTML] Impact of radiation dose distribution on nutritional supplementation needs in head and neck cancer radiotherapy: a voxel-based machine learning approach

S Madhavan, M Gamez, YI Garces, SC Lester… - Frontiers in …, 2024 - frontiersin.org
Objectives To investigate the relationship between nutritional supplementation and radiation
dose to the pharyngeal constrictor muscles and larynx for head and neck (HN) cancer …