Aortic dissection is a critical cardiovascular disease due to the separation of media and
adventitia caused by the rupture of vascular wall intima. The disease has a high mortality …

Smooth muscle cell (SMC) loss is the characteristic feature in the pathogenesis of aortic
dissection (AD), and ferroptosis is a novel iron-dependent regulated cell death driven by the …

Regulated cell death (RCD) is a basic biological phenomenon associated with cell and
tissue homeostasis. Recent studies have enriched our understanding of RCD, and many …

Aortic dissection (AD) presents a medical challenge for clinicians. Here, to determine the
role of a novel small non-coding piRNA-823 (piR-823) in AD, murine and human aorta from …

Iron functions as an essential micronutrient and participates in normal physiological and
biochemical processes in the cardiovascular system. Ferroptosis is a novel type of iron …

Background Aortic dissection (AD) is a macrovascular disease which is pathologically
characterized by aortic media degeneration (AMD). Our team's previous research found that …

Essential trace elements play an important role in human physiology and are associated
with various functions regulating cellular metabolism. Non-essential trace elements, on the …

Iron plays a crucial role in many physiological processes, including oxygen transport,
bioenergetics, and immune function. Iron is assimilated from food and also recycled from …

Background Cerebral blood flow (CBF) and susceptibility values reflect vascular and iron
metabolism, providing mechanistic insights into conditions of health and disease …

Vascular inflammation triggers the development of thoracic aortic dissection (TAD). Zinc
deficiency could dampen tissue inflammation. However, the role of zinc as a nutritional …