Modulation of nitric oxide synthases by oxidized LDLs: role in vascular inflammation and atherosclerosis development

M Gliozzi, M Scicchitano, F Bosco, V Musolino… - International journal of …, 2019 - mdpi.com
The maintenance of physiological levels of nitric oxide (NO) produced by eNOS represents a
key element for vascular endothelial homeostasis. On the other hand, NO overproduction …

The dual personality of NO

M Colasanti, H Suzuki - Trends in pharmacological sciences, 2000 - cell.com
In the body, nitric oxide (NO) is an important physiological regulator of functions such as
vasodilatation and neurotransmission. Under pathological conditions, high concentrations of …

Extracellular signal-regulated kinase and p38 subgroups of mitogen-activated protein kinases regulate inducible nitric oxide synthase and tumor necrosis factor-α …

NR Bhat, P Zhang, JC Lee, EL Hogan - Journal of Neuroscience, 1998 - Soc Neuroscience
Tumor necrosis factor-α (TNFα) and nitric oxide (NO), the product of inducible NO synthase
(iNOS), mediate inflammatory and immune responses in the CNS under a variety of …

Immune function of endothelial cells: evolutionary aspects, molecular biology and role in atherogenesis

S Kotlyarov - International Journal of Molecular Sciences, 2022 - mdpi.com
Atherosclerosis is one of the key problems of modern medicine, which is due to the high
prevalence of atherosclerotic cardiovascular diseases and their significant share in the …

[HTML][HTML] Nitric oxide mediates anti-inflammatory action of extracorporeal shock waves

AR Ciampa, AC de Prati, E Amelio, E Cavalieri… - FEBS letters, 2005 - Elsevier
Here, we show that extracorporeal shock waves (ESW), at a low energy density value,
quickly increase neuronal nitric oxide synthase (nNOS) activity and basal nitric oxide (NO) …

[PDF][PDF] Immune processes in the pathogenesis of Parkinson's disease-a potential role for microglia and nitric oxide

A Czlonkowska, I Kurkowska-Jastrzebska… - Medical Science …, 2002 - researchgate.net
It has been known for many years that immune system alterations occur in Parkinson's
disease (PD). Changes in lymphocyte populations in cerebrospinal fluid and blood …

Induction of Nitric Oxide in Human Monocytes and Monocyte Cell Lines byMycobacterium tuberculosis

C Jagannath, JK Actor, RL Hunter Jr - Nitric oxide, 1998 - Elsevier
The induction of nitric oxide in human monocytes during mycobacterial infection has been a
controversial issue. This study describes a comparative evaluation of the colorimetric and …

Nitric oxide: an inhibitor of NF-κB/Rel system in glial cells

M Colasanti, T Persichini - Brain research bulletin, 2000 - Elsevier
Nitric oxide (NO) has been reported to regulate NF-κB, one of the best-characterized
transcription factors playing important roles in many cellular responses to a large variety of …

Neuronal nitric oxide synthase (NOS) regulates the expression of inducible NOS in rat small intestine via modulation of nuclear factor kappa B

XWU QU, HAO Wang, IG De Plaen… - The FASEB …, 2001 - Wiley Online Library
We previously reported that neuronal nitric oxide synthase (nNOS) is the predominant NOS
in the intestine. Inducible NOS (iNOS), an enzyme involved in the inflammatory response, is …

Cross-talk between constitutive and inducible NO synthase: an update

T Persichini, O Cantoni, H Suzuki… - Antioxidants & redox …, 2006 - liebertpub.com
Inducible nitric oxide synthase (iNOS) is expressed upon exposure of some cell types to
bacterial lipopolysaccharides (LPS) and/or a variety of proinflammatory cytokines. The …