Structural insights into viral genome replication by the severe fever with thrombocytopenia syndrome virus L protein
HM Williams, SR Thorkelsson, D Vogel… - Nucleic acids …, 2023 - academic.oup.com
Severe fever with thrombocytopenia syndrome virus (SFTSV) is a phenuivirus that has
rapidly become endemic in several East Asian countries. The large (L) protein of SFTSV …
rapidly become endemic in several East Asian countries. The large (L) protein of SFTSV …
Viral RNA capping: Mechanisms and antiviral therapy
S Chen, Z Jiang, Q Li, W Pan, Y Chen… - Journal of Medical …, 2024 - Wiley Online Library
RNA capping is an essential trigger for protein translation in eukaryotic cells. Many viruses
have evolved various strategies for initiating the translation of viral genes and generating …
have evolved various strategies for initiating the translation of viral genes and generating …
Crystal structures of flavivirus NS5 Guanylyltransferase reveal a GMP-arginine adduct
H Jia, Y Zhong, C Peng, P Gong - Journal of virology, 2022 - Am Soc Microbiol
The positive-sense flavivirus RNA genome bears a cap 1 structure essential for RNA stability
and viral protein translation, and the formation of cap 1 requires the virally encoded …
and viral protein translation, and the formation of cap 1 requires the virally encoded …
[PDF][PDF] Biophysical and structural study of La Crosse virus endonuclease inhibition for the development of new antiviral options
M Feracci, S Hernandez, L Garlatti, C Mondielli… - IUCrJ, 2024 - journals.iucr.org
The large Bunyavirales order includes several families of viruses with a segmented
ambisense (−) RNA genome and a cytoplasmic life cycle that starts by synthesizing viral …
ambisense (−) RNA genome and a cytoplasmic life cycle that starts by synthesizing viral …
[HTML][HTML] A novel chimeric RNA originating from BmCPV S4 and Bombyx mori HDAC11 transcripts regulates virus proliferation
J Pan, S Wei, Q Qiu, X Tong, Z Shen, M Zhu, X Hu… - Plos …, 2023 - journals.plos.org
Polymerases encoded by segmented negative-strand RNA viruses cleave 5'-m7G-capped
host transcripts to prime viral mRNA synthesis (“cap-snatching”) to generate chimeric RNA …
host transcripts to prime viral mRNA synthesis (“cap-snatching”) to generate chimeric RNA …
Structural and Biochemical Basis for Development of Diketo Acid Inhibitors Targeting the Cap-Snatching Endonuclease of the Ebinur Lake Virus (Order: Bunyavirales …
W Kuang, H Zhang, Y Cai, G Zhang, F Deng… - Journal of …, 2022 - Am Soc Microbiol
The Bunyavirales contain many important human pathogens that lack an antiviral therapy.
The cap-snatching endonuclease (EN) of segmented negative-strand RNA viruses is an …
The cap-snatching endonuclease (EN) of segmented negative-strand RNA viruses is an …