Two decades ago successful transfection of antigen presenting cells (APC) in vivo was
demonstrated which resulted in the induction of primary adaptive immune responses. Due to …

Helicobacter pylori is a gastric pathogen that colonizes approximately 50% of the world's
population. Infection with H. pylori causes chronic inflammation and significantly increases …

Helicobacter pylori is the first formally recognized bacterial carcinogen and is one of the
most successful human pathogens, as over half of the world's population is colonized with …

C-type lectin receptors (CLRs) expressed by dendritic cells are crucial for tailoring immune
responses to pathogens. Following pathogen binding, CLRs trigger distinct signalling …

Carbohydrates are the most abundant natural products. Besides their role in metabolism
and as structural building blocks, they are fundamental constituents of every cell surface …

The importance of protein glycosylation in the migration of immune cells throughout the body
has been extensively appreciated. However, our awareness of the impact of glycosylation …

Dendritic cells (DCs) are crucial in the defence against pathogens. Invading pathogens are
recognized by Toll-like receptors (TLRs) and receptors such as C-type lectins expressed on …

BACKGROUND: Lactobacilli are probiotic bacteria that are frequently tested in the
management of allergic diseases or gastroenteritis. It is hypothesized that these probiotics …

C-type lectin receptors (CLRs) are important pattern recognition receptors involved in
recognition and induction of adaptive immunity to pathogens. Certain CLRs play an …

Both the dendritic cell receptor DC-SIGN and the closely related endothelial cell receptor DC-
SIGNR bind human immunodeficiency virus and enhance infection. However, biochemical …