Epigenetic clocks comprise a set of CpG sites whose DNA methylation levels measure
subject age. These clocks are acknowledged as a highly accurate molecular correlate of …

Acute inflammation is a physiological response to injury or infection, with a cascade of steps
that ultimately lead to the recruitment of immune cells to clear invading pathogens and heal …

Biological aging of human organ systems reflects the interplay of age, chronic disease,
lifestyle and genetic risk. Using longitudinal brain imaging and physiological phenotypes …

Advanced age is the main common risk factor for cancer, cardiovascular disease and
neurodegeneration. Yet, more is known about the molecular basis of any of these groups of …

Historically, systemic self-inflammatory conditions were classified as either autoinflammatory
and caused by the innate immune system or autoimmune and driven by adaptive immune …

Aging as an irretrievable occurrence throughout the entire life is characterized by a
progressive decline in physiological functionality and enhanced disease vulnerability …

Many studies have reported age-associated DNA methylation changes and age-predictive
models in various tissues and body fluids. Although age-associated DNA methylation …

Epigenetic alterations and metabolic dysfunction are two hallmarks of aging. However, the
mechanism of how their interaction regulates aging, particularly in mammals, remains …

Abstract Forensic DNA Phenotyping (FDP) comprises the prediction of a person's externally
visible characteristics regarding appearance, biogeographic ancestry and age from DNA of …

DNA methylation is known as a biomarker for age with applications in forensics. Here we
describe the VISAGE (VISible Attributes through GEnomics) Consortium's enhanced tool for …