Functions and consequences of AID/APOBEC-mediated DNA and RNA deamination
R Pecori, S Di Giorgio, J Paulo Lorenzo… - Nature Reviews …, 2022 - nature.com
The AID/APOBEC polynucleotide cytidine deaminases have historically been classified as
either DNA mutators or RNA editors based on their first identified nucleic acid substrate …
either DNA mutators or RNA editors based on their first identified nucleic acid substrate …
Active DNA demethylation: many roads lead to Rome
SC Wu, Y Zhang - Nature reviews Molecular cell biology, 2010 - nature.com
DNA methylation is one of the best-characterized epigenetic modifications and has been
implicated in numerous biological processes, including transposable element silencing …
implicated in numerous biological processes, including transposable element silencing …
DART-seq: an antibody-free method for global m6A detection
KD Meyer - Nature methods, 2019 - nature.com
Abstract N 6-methyladenosine (m6A) is a widespread RNA modification that influences
nearly every aspect of the messenger RNA lifecycle. Our understanding of m6A has been …
nearly every aspect of the messenger RNA lifecycle. Our understanding of m6A has been …
Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2)
The activation-induced cytidine deaminase (AID) gene, specifically expressed in germinal
center B cells in mice, is a member of the cytidine deaminase family. We herein report …
center B cells in mice, is a member of the cytidine deaminase family. We herein report …
Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cells
M Muramatsu, VS Sankaranand, S Anant… - Journal of Biological …, 1999 - ASBMB
We have identified a novel gene referred to asactivation-induced deaminase (AID) by
subtraction of cDNAs derived from switch-induced and uninduced murine B lymphoma …
subtraction of cDNAs derived from switch-induced and uninduced murine B lymphoma …
Epigenetic reprogramming in mouse pre-implantation development and primordial germ cells
M Saitou, S Kagiwada, K Kurimoto - Development, 2012 - journals.biologists.com
Epigenetic modifications are crucial for the identity and stability of cells, and, when aberrant,
can lead to disease. During mouse development, the genome-wide epigenetic states of pre …
can lead to disease. During mouse development, the genome-wide epigenetic states of pre …
Recent advances in zinc enzymology
WN Lipscomb, N Sträter - Chemical Reviews, 1996 - ACS Publications
Posters and lectures presented at the Seventh International Conference on Bioinorganic
Chemistry (ICBIC) in Lubeck, Germany, last year was divided into 16 sections, including …
Chemistry (ICBIC) in Lubeck, Germany, last year was divided into 16 sections, including …
The AID/APOBEC family of nucleic acid mutators
SG Conticello - Genome biology, 2008 - Springer
The AID/APOBECs, a group of cytidine deaminases, represent a somewhat unusual protein
family that can insert mutations in DNA and RNA as a result of their ability to deaminate …
family that can insert mutations in DNA and RNA as a result of their ability to deaminate …
An anthropoid-specific locus of orphan C to U RNA-editing enzymes on chromosome 22
A Jarmuz, A Chester, J Bayliss, J Gisbourne, I Dunham… - Genomics, 2002 - Elsevier
The cytidine (C) to uridine (U) editing of apolipoprotein (apo) B mRNA is mediated by tissue-
specific, RNA-binding cytidine deaminase APOBEC1. APOBEC1 is structurally homologous …
specific, RNA-binding cytidine deaminase APOBEC1. APOBEC1 is structurally homologous …
Evolution of the AID/APOBEC family of polynucleotide (deoxy) cytidine deaminases
SG Conticello, CJF Thomas… - Molecular biology …, 2005 - academic.oup.com
The AID/APOBEC family (comprising AID, APOBEC1, APOBEC2, and APOBEC3 subgroups)
contains members that can deaminate cytidine in RNA and/or DNA and exhibit diverse …
contains members that can deaminate cytidine in RNA and/or DNA and exhibit diverse …