Ethnopharmacological relevance The bidirectional property of traditional Chinese medicines
(TCMs) was recorded in the classic work Medicine Origin (Yi Xue Qi Yuan) as early as the …

Background: Chinese herbal medicine (CHM) provides a theoretical basis for the treatment
of psoriasis with considerable benefits and a low toxicity. The purpose of this quantitative …

Psoriasis does not respond adequately to the monotherapy, tailoring combined strategies for
synergistical treatment remains challenging. We fabricated chitosan/hyaluronan nanogels to …

Immune-mediated inflammation contributes to the development of psoriasis. However, long-
term treatment with global immunosuppressive agents may cause a variety of side effects …

Psoriasis is an immune-mediated systemic disease that may be treated with probiotics. In
this study, probiotic strains that could or could not decrease interleukin (IL)-17 levels were …

First-line treatments for mild to moderate psoriasis are typically topical formulations
containing corticosteroids, however, the therapeutic efficacy of these formulations is …

Diabetic ulcers (DUs), a devastating complication of diabetes, are intractable for limited
effective interventions in clinic. Based on the clinical samples and bioinformatic analysis, we …

Rheumatoid arthritis (RA) is an autoimmune disease with increased M1 macrophages. The
classical activated M1 macrophages produce various cytokines to control inflammation …

Background Psoriasis is an autoimmune disease mediated by T cells. However, treatment
remains a clinical challenge because of its frequent recurrence. Celastrol (Cel), the main …

The treatment of glioblastoma multiforme (GBM) is challenging owing to its localization in the
brain, the limited capacity of brain cells to repair, resistance to conventional therapy, and its …