Viscoelastic hemostatic assays: a primer on legacy and new generation devices

O Volod, CM Bunch, N Zackariya, EE Moore… - Journal of Clinical …, 2022 - mdpi.com
Viscoelastic hemostatic assay (VHAs) are whole blood point-of-care tests that have become
an essential method for assaying hemostatic competence in liver transplantation, cardiac …

[HTML][HTML] Viscoelastic testing: an illustrated review of technology and clinical applications

J Hartmann, D Hermelin, JH Levy - Research and Practice in Thrombosis …, 2023 - Elsevier
Viscoelastic testing (VET), including thromboelastography and thromboelastometry,
provides a rapid and comprehensive picture of whole blood coagulation dynamics and …

Detection of cellular traction forces via the force-triggered Cas12a-mediated catalytic cleavage of a fluorogenic reporter strand

Y Duan, F Szlam, Y Hu, W Chen, R Li, Y Ke… - Nature Biomedical …, 2023 - nature.com
Molecular forces generated by cell receptors are infrequent and transient, and hence difficult
to detect. Here we report an assay that leverages the CRISPR-associated protein 12a …

Viscoelastic hemostatic assays: moving from the laboratory to the site of care—a review of established and emerging technologies

J Hartmann, M Murphy, JD Dias - Diagnostics, 2020 - mdpi.com
Viscoelastic-based techniques to evaluate whole blood hemostasis have advanced
substantially since they were first developed over 70 years ago but are still based upon the …

Prognostic impact of hypercoagulability and impaired fibrinolysis in acute myocardial infarction

SH Lee, HK Kim, JH Ahn, MG Kang… - European Heart …, 2023 - academic.oup.com
Aims Atherothrombotic events are influenced by systemic hypercoagulability and fibrinolytic
activity. The present study evaluated thrombogenicity indices and their prognostic …

Reversal and removal of oral antithrombotic drugs in patients with active or perceived imminent bleeding

D Cao, N Amabile, M Chiarito, VT Lee… - European Heart …, 2023 - academic.oup.com
Remarkable progress has been made in the pharmacological management of patients with
cardiovascular disease, including the frequent use of antithrombotic agents. Nonetheless …

Viscoelastic testing and coagulopathy of traumatic brain injury

JL Bradbury, SG Thomas, NR Sorg, N Mjaess… - Journal of clinical …, 2021 - mdpi.com
A unique coagulopathy often manifests following traumatic brain injury, leading the clinician
down a difficult decision path on appropriate prophylaxis and therapy. Conventional …

TEG® 6s system measures the contributions of both platelet count and platelet function to clot formation at the site-of-care

JD Dias, CG Lopez-Espina, K Bliden, P Gurbel… - Platelets, 2020 - Taylor & Francis
Abstract Knowledge of platelet count and function is key to ensuring appropriate hemostatic
management. We hypothesized that the novel, portable TEG® 6s coagulation assessment …

The role of viscoelastic testing in assessing peri-interventional platelet function and coagulation

US Tantry, J Hartmann, MD Neal, H Schöechl… - Platelets, 2022 - Taylor & Francis
We carried out a literature search in MEDLINE (PubMed) and EMBASE literature databases
to provide a concise review of the role of viscoelastic testing in assessing peri-interventional …

Advances in Platelet-Dysfunction Diagnostic Technologies

I Yoon, JH Han, HJ Jeon - Biomolecules, 2024 - mdpi.com
The crucial role of platelets in hemostasis and their broad implications under various
physiological conditions underscore the importance of accurate platelet-function testing …