Layered double hydroxides (LDHs), also known as anionic clays, have attracted significant
attention in energy and environmental applications due to their exceptional physicochemical …

Feeding the ever-growing population is a major challenge, especially in light of rapidly
changing climate conditions. Genome editing is set to revolutionize plant breeding and …

The development of CRISPR–Cas systems has sparked a genome editing revolution in
plant genetics and breeding. These sequence-specific RNA-guided nucleases can induce …

The prokaryote-derived CRISPR–Cas genome editing technology has altered plant
molecular biology beyond all expectations. Characterized by robustness and high target …

Prime editing is a versatile genome-editing technology, but it suffers from low editing
efficiency. In the present study, we introduce optimized prime editors with substantially …

The development of new CRISPR–Cas genome editing tools continues to drive major
advances in the life sciences. Four classes of CRISPR–Cas-derived genome editing agents …

Cultivated rice varieties are all diploid, and polyploidization of rice has long been desired
because of its advantages in genome buffering, vigorousness, and environmental …

The elucidation of protein function and its exploitation in bioengineering have greatly
advanced the life sciences. Protein mining efforts generally rely on amino acid sequences …

Prime editors, which are CRISPR–Cas9 nickase (H840A)–reverse transcriptase fusions
programmed with prime editing guide RNAs (pegRNAs), can edit bases in mammalian cells …

Based on engineered or bacterial nucleases, the development of genome editing
technologies has opened up the possibility of directly targeting and modifying genomic …