Ultrasound therapy has a long history of novel applications in medicine. Compared to high-
intensity ultrasound used for tissue heating, low-intensity ultrasound has drawn increasing …

Macrophages are tissue-resident immune cells that play a critical role in maintaining
homeostasis and fighting infection. In addition, these cells are involved in the progression of …

IL-17 is a newly described, T cell-derived cytokine with ill-defined physiologic properties. As
such, we examined the release of proinflammatory mediators by human macrophages in …

Low‐intensity pulsed ultrasound (LIPUS) has been shown to accelerate fracture healing in
both animal models and clinical trials, but the mechanism of action remains unclear. In …

Lipopolysaccharide (LPS) represents a major virulence factor of Gram‐negative bacteria
('endotoxin') that can cause septic shock in mammals including man. The lipid anchor of LPS …

Artificial mechanical ventilation represents a major cause of iatrogenic lung damage in
intensive care. It is largely unknown which mediators, if any, contribute to the onset of such …

Atherosclerotic vascular disease is the most common cause of morbidity and mortality in
developed countries, and the world-wide importance of acute vascular syndromes is …

Recent clinical trials have shown that the survival of patients with acute respiratory distress
syndrome (ARDS) is improved by ventilation with reduced volumes. These studies …

Ion channels are known to be present on the plasma membrane of virtually all cells and
have been found on the membranes of various intracellular organelles. However, until …

Molecules of endotoxin (lipopolysaccharides, LPS), forming a unique molecular class with
peculiar physicochemical properties, impart a very important role in the formation and …