Neutrophil extracellular trap (NET) formation, first described in 2004 as a previously
unknown strategy of neutrophils to fight microbes, has attracted an increasing interest in the …

Systemic lupus erythematosus (SLE), often considered the prototype of autoimmune
diseases, is characterized by over-activation of the autoimmune system with abnormal …

In this review, we examine the evidence that neutrophil extracellular traps (NETs) play a
critical role in innate immunity. We summarize how NETs are formed in response to various …

Systemic lupus erythematosus (SLE) is an autoimmune disease in which patients develop
autoantibodies to DNA, histones, and often to neutrophil proteins. These form immune …

SLE is a chronic autoimmune disease caused by perturbations of the immune system. The
clinical presentation is heterogeneous, largely because of the multiple genetic and …

Systemic Lupus Erythematosus (SLE) is characterized by a wide spectrum of auto-
antibodies which recognize several cellular components. The production of these self …

Lupus nephritis (LN) is a common complication of systemic lupus erythematosus (SLE) and
a major risk factor for morbidity and mortality. The abundant cell-free nucleic (DNA/RNA) in …

Human matrix metalloproteinases (MMPs) belong to the M10 family of the MA clan of
endopeptidases. They are ubiquitarian enzymes, structurally characterized by an active site …

Circulating cell-free DNA is considered as one of the major breakthroughs in the field of
innovative diagnosis, used as a liquid biopsy. The kinetic parameters of a biomarker are …

Systemic lupus erythematosus is a multifactorial autoimmune disease with an as yet
unknown etiopathogenesis. It is widely thought that self-immunization in systemic lupus is …