[HTML][HTML] Adult mesenchymal stem cells from oral cavity and surrounding areas: types and biomedical applications

ME Cabaña-Muñoz, MJ Pelaz Fernández… - Pharmaceutics, 2023 - mdpi.com
Adult mesenchymal stem cells are those obtained from the conformation of dental structures
(DMSC), such as deciduous and permanent teeth and other surrounding tissues …

[HTML][HTML] Analogies and differences between dental stem cells: Focus on secretome in combination with scaffolds in neurological disorders

F Santilli, J Fabrizi, C Santacroce, D Caissutti… - Stem Cell Reviews and …, 2024 - Springer
Mesenchymal stem cells (MSCs) are well known for their beneficial effects, differentiation
capacity and regenerative potential. Dental-derived MSCs (DSCs) are more easily …

[HTML][HTML] The importance of stem cells isolated from human dental pulp and exfoliated deciduous teeth as therapeutic approach in nervous system pathologies

N Candelise, F Santilli, J Fabrizi, D Caissutti, Z Spinello… - Cells, 2023 - mdpi.com
Despite decades of research, no therapies are available to halt or slow down the course of
neuro-degenerative disorders. Most of the drugs developed to fight neurodegeneration are …

[HTML][HTML] Huntington's Disease Drug Development: A Phase 3 Pipeline Analysis

HJ Van de Roovaart, N Nguyen, TD Veenstra - Pharmaceuticals, 2023 - mdpi.com
Huntington's Disease (HD) is a severely debilitating neurodegenerative disorder in which
sufferers exhibit different combinations of movement disorders, dementia, and behavioral or …

[HTML][HTML] Insulin promotes the bone formation capability of human dental pulp stem cells through attenuating the IIS/PI3K/AKT/mTOR pathway axis

Y Shan, Y Luo, Y Dai, M Gao, Y Lv, C Zhang… - Stem Cell Research & …, 2024 - Springer
Background Insulin has been known to regulate bone metabolism, yet its specific molecular
mechanisms during the proliferation and osteogenic differentiation of dental pulp stem cells …

[HTML][HTML] The effect of adjunctive LASER application on periodontal ligament stem cells

D Ponnaiyan, RR Rughwani, G Shetty… - Frontiers in Cell and …, 2024 - frontiersin.org
Periodontal regeneration involves the composite action of cell, scaffolds and signaling
molecules. There are numerous autologous sources of regenerative cells which are present …

[HTML][HTML] Dental pulp stem cells ameliorate D-galactose-induced cardiac ageing in rats

G El-Akabawy, SOF El-Kersh, AOFO El-Kersh, SN Amin… - PeerJ, 2024 - peerj.com
Background Ageing is a key risk factor for cardiovascular disease and is linked to several
alterations in cardiac structure and function, including left ventricular hypertrophy and …

Human striatal progenitor cells that contain inducible safeguards and overexpress BDNF rescue Huntington's disease phenotypes in R6/2 mice

DA Simmons, S Selvaraj, T Chen, G Cao… - bioRxiv, 2024 - biorxiv.org
Huntington's disease (HD) is an autosomal-dominant neurodegenerative disorder
characterized by striatal atrophy. Reduced trophic support due to decreased striatal levels of …

Exploring the Nexus between Dental Stem Cells and Maternal Oral Health during Pregnancy: What We Know and What We Don't

A Meto, A Sula, S Peppoloni, A Meto, E Blasi - 2024 - preprints.org
During pregnancy, profound physiological changes occur in the maternal body, including
those affecting oral health. Dental stem cells (DSCs) have emerged as promising candidates …

[HTML][HTML] How Far Are We from Regrowing Teeth, and What Are the Other Options?

T Lively - dentalproductsreport.com
Dental material companies work to create restorative materials that mimic the behavior,
function, and esthetics of natural teeth. Many of them do an excellent job, performing …