Salmonella in Swine: Prevalence, Multidrug Resistance, and Vaccination Strategies

SMD Bearson - Annual review of animal biosciences, 2022 - annualreviews.org
An estimated 1.3 million Salmonella infections and 420 deaths occur annually in the United
States, with an estimated economic burden of $3.7 billion. More than 50% of US swine …

Review of methods for the detection of Lawsonia intracellularis infection in pigs

M Campillo, SH Smith, DL Gally… - Journal of Veterinary …, 2021 - journals.sagepub.com
Lawsonia intracellularis is an obligate intracellular bacterium associated with enteric
disease in pigs. Clinical signs include weight loss, diarrhea, and, in some cases, sudden …

Self− Assembling Nanovaccine Fused with Flagellin Enhances Protective Effect against Foot− and− Mouth Disease Virus

C Pei, H Dong, Z Teng, S Wei, Y Zhang, S Yin, J Tang… - Vaccines, 2023 - mdpi.com
Nanovaccines based on self− assembling nanoparticles (NPs) can show conformational
epitopes of antigens and they have high immunogenicity. In addition, flagellin, as a …

[HTML][HTML] Effect of dietary β-glucan on intestinal microbial diversity and Salmonella vaccine immunogenicity and efficacy in pigs

CL Loving, SMD Bearson, BL Bearson, BJ Kerr… - Veterinary …, 2023 - Elsevier
Alternatives to antibiotics to improve animal performance, limit the negative impact of
infectious disease, and/or reduce colonization with foodborne pathogens is a major focus of …

Porcine Response to a Multidrug-Resistant Salmonella enterica serovar I 4,[5],12:i:- Outbreak Isolate

DC Shippy, BL Bearson, DB Holman… - Foodborne …, 2018 - liebertpub.com
Abstract Salmonella enterica serovar I 4,[5], 12: i:-has emerged as a common nontyphoidal
Salmonella serovar to cause human foodborne illness. An interesting trait of serovar I 4,[5] …

A rationally designed oral vaccine induces immunoglobulin A in the murine gut that directs the evolution of attenuated Salmonella variants

M Diard, E Bakkeren, V Lentsch, A Rocker… - Nature …, 2021 - nature.com
The ability of gut bacterial pathogens to escape immunity by antigenic variation—particularly
via changes to surface-exposed antigens—is a major barrier to immune clearance …

Effects of β-glucan on Salmonella enterica serovar Typhimurium swine colonization and microbiota alterations

SMD Bearson, JM Trachsel, BL Bearson… - Porcine Health …, 2023 - Springer
Abstract Background The 2017 Veterinary Feed Directive eliminated the use of medically
important antibiotics for growth promotion of food animals; thus, alternative growth promoters …

T-Cell Cytokine Response in Salmonella Typhimurium-Vaccinated versus Infected Pigs

S Schmidt, H Kreutzmann, M Stadler, KH Mair, MR Stas… - Vaccines, 2021 - mdpi.com
Vaccination with the live attenuated vaccine Salmoporc is an effective measure to control
Salmonella Typhimurium (STM) in affected swine populations. However, the cellular …

Microfluidic dual-mode detection system for multiple foodborne pathogens using phage-aptamer-DNAzyme composite encoded probes

S Zhu, S Wang, Y Wang, Q Liu, T Li, N Gan - Microchemical Journal, 2025 - Elsevier
In the field of food safety testing, a rapid, accurate and cost-effective method for monitoring
multiple pathogenic bacteria is urgently required. In this study, a composite probe …

Chlortetracycline Enhances Tonsil Colonization and Fecal Shedding of Multidrug-Resistant Salmonella enterica Serovar Typhimurium DT104 without Major …

DB Holman, BL Bearson, HK Allen… - Applied and …, 2019 - Am Soc Microbiol
Salmonella spp. are estimated to cause 1.2 million cases of human foodborne illness each
year in the United States, and pigs can often be asymptomatically colonized with Salmonella …