Different blood flow patterns in the arteries can alter the adaptive phenotype of vascular
endothelial cells (ECs), thereby affecting the functions of ECs and are directly associated …

Hypohydration, defined as a state of low body water, increases thirst sensations, arginine
vasopressin release, and elicits renin–angiotensin–aldosterone system activation to …

Antibody use is a critical component of cardiovascular physiology research, and antibodies
are used to monitor protein abundance (immunoblot analysis) and protein expression and …

The problem of inadequate statistical reporting is long standing and widespread in the
biomedical literature, including in cardiovascular physiology. Although guidelines for …

Endothelial dysfunction and arterial stiffness are nontraditional risk factors of chronic kidney
disease (CKD)-related cardiovascular disease (CVD) that could be targeted with exercise …

Objective: To determine if endothelial dysfunction in a mouse model of diet-induced obesity
and in obese humans is mediated by the suppression of endothelial Kir (inwardly rectifying …

Background Hypercholesterolemia‐induced decreased availability of nitric oxide (NO) is a
major factor in cardiovascular disease. We previously established that cholesterol …

Obesity imposes well-established deficits to endothelial function. We recently showed that
obesity-induced endothelial dysfunction was mediated by disruption of the glycocalyx and a …

Dyslipidemia-induced endothelial dysfunction is an important factor in the progression of
cardiovascular disease; however, the underlying mechanisms are unclear. Our recent …

Hypertension is associated with decreased endothelial function through reduced
contributions of nitric oxide (NO). We previously discovered that flow-induced NO production …