Protoporphyrinogen oxidase inhibitor: an ideal target for herbicide discovery

GF Hao, Y Zuo, SG Yang, GF Yang - Chimia, 2011 - chimia.ch
As the last common enzyme in the biosynthetic pathway leading to heme and chlorophyll,
protoporphyrinogen oxidase (PPO; EC 1.3. 3.4) is an ideal target for herbicide development …

Design, synthesis, and herbicidal activity of diphenyl ether derivatives containing a five-membered heterocycle

LX Zhao, JF Peng, FY Liu, YL Zou, S Gao… - Journal of Agricultural …, 2022 - ACS Publications
Protoporphyrinogen oxidase (PPO, EC 1.3. 3.4) is an important target for discovering novel
herbicides, and it causes bleaching symptoms by inhibiting the synthesis of chlorophyll and …

Synthesis, Herbicidal Activity, and QSAR of Novel N-Benzothiazolyl- pyrimidine-2,4-diones as Protoporphyrinogen Oxidase Inhibitors

Y Zuo, Q Wu, S Su, C Niu, Z Xi… - Journal of agricultural and …, 2016 - ACS Publications
Protoporphyrinogen oxidase (PPO, EC 1.3. 3.4) is known as a key action target for several
structurally diverse herbicides. As a continuation of our research work on the development of …

Potentials of diphenyl ether scaffold as a therapeutic agent: A review

SG Kini, E Rathi, A Kumar, V Bhat - Mini reviews in medicinal …, 2019 - ingentaconnect.com
Diphenyl ethers (DPE) and its analogs have exhibited excellent potential for therapeutic and
industrial applications. Since the 19th century, intensive research is perpetuating on the …

A nitroreductase DnrA catalyzes the biotransformation of several diphenyl ether herbicides in Bacillus sp. Za

Y Tian, G Zhao, M Cheng, L Lu, H Zhang… - Applied Microbiology and …, 2023 - Springer
Diphenyl ether herbicides, typical globally used herbicides, threaten the agricultural
environment and the sensitive crops. The microbial degradation pathways of diphenyl ether …

Virtual screening of natural products against 5-enolpyruvylshikimate-3-phosphate synthase using the Anagreen herbicide-like natural compound library

MVD de Oliveira, GMB Fernandes, KS da Costa… - RSC …, 2022 - pubs.rsc.org
The shikimate pathway enzyme 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS)
catalyzes a reaction involved in the production of amino acids essential for plant growth and …

Quantitative structure activity relationship studies and molecular dynamics simulations of 2-(aryloxyacetyl) cyclohexane-1, 3-diones derivatives as 4 …

Y Fu, YX Liu, KH Yi, MQ Li, JZ Li, F Ye - Frontiers in Chemistry, 2019 - frontiersin.org
4-Hydroxyphenylpyruvate dioxygenase (HPPD) is a significant enzyme in the biosynthesis
of plastoquinone and tocopherol. Moreover, it is also a potential target to develop new …

Design and synthesis of 1-(benzothiazol-5-yl)-1H-1, 2, 4-triazol-5-ones as protoporphyrinogen oxidase inhibitors

Z Yang, Y Sheng-Gang, L Yan-Ping, T Ying… - Bioorganic & medicinal …, 2013 - Elsevier
Protoporphyrinogen oxidase (PPO, EC 1.3. 3.4) is the action target for several structurally
diverse herbicides. A series of novel 4-(difluoromethyl)-1-(6-halo-2-substituted-benzothiazol …

[HTML][HTML] MPoMA protects against lung epithelial cell injury via p65 degradation

S Lee, SJ Yoon, JH Oh, JS Ryu, Y Park… - Biomedicine & …, 2024 - Elsevier
Numerous cases of lung injury caused by viral infection were reported during the
coronavirus disease-19 pandemic. While there have been significant efforts to develop …

Computational and experimental insights into the mechanism of substrate recognition and feedback inhibition of protoporphyrinogen oxidase

GF Hao, Y Tan, SG Yang, ZF Wang, CG Zhan, Z Xi… - PloS one, 2013 - journals.plos.org
Protoporphyrinogen IX oxidase (PPO; EC 1.3. 3.4) is an essential enzyme catalyzing the last
common step in the pathway leading to heme and chlorophyll biosynthesis. Great interest in …