The entry of enveloped viruses into its host cells is a crucial step for the propagation of viral
infection. The envelope glycoprotein complex controls viral tropism and promotes the …

The physiological role of the subtilisin/kexin‐like proprotein convertases (PCs) in rodents
has been examined through the use of knockout mice. This review will summarize the major …

To investigate the evolutionary history of the recent outbreak of severe acute respiratory
syndrome coronavirus 2 (SARS‐CoV‐2) in China, a total of 70 genomes of virus strains from …

ABSTRACT Tetherin (CD317/BST-2), an interferon-induced membrane protein, restricts the
release of nascent retroviral particles from infected cell surfaces. While human …

In virus-infected cells, the envelope glycoprotein (Env) precursor, gp160, of human
immunodeficiency virus type 1 is cleaved by cellular proteases into a fusion-competent …

Human immunodeficiency virus binds and enters cells via the Envelope glycoprotein gp160
at its surface. In infected cells, gp160 is found not only on the plasma membrane but also in …

HIV/AIDS is still a global threat despite the notable efforts made by the scientific and health
communities to understand viral infection, to design new drugs or to improve existing ones …

Progress in developing effective gene transfer approaches to treat HIV-1 infection has been
steady. Many different transgenes have been reported to inhibit HIV-1 in vitro. However …

A major portion of the human genome appears to be of retroviral origin. These endogenous
retroviral elements are expressed in a variety of normal tissues and during disease states …

Endoproteolytic processing of the human immunodeficiency virus type 1 (HIV-1) envelope
(Env) glycoproteins is an obligate part of the biosynthetic pathway that generates functional …