[HTML][HTML] Therapeutic Exploitation of Neuroendocrine Transdifferentiation Drivers in Prostate Cancer

ZR Maylin, C Smith, A Classen, M Asim, H Pandha… - Cells, 2024 - mdpi.com
Neuroendocrine prostate cancer (NEPC), an aggressive and lethal subtype of prostate
cancer (PCa), often arises as a resistance mechanism in patients undergoing hormone …

ZBTB7A as a therapeutic target for cancer

Y Zhou, X Chen, X Zu - Biochemical and Biophysical Research …, 2024 - Elsevier
ZBTB7A, alternatively referred to Pokemon, FBI-1, LRF, and OCZF, is classified as a member
of POK/ZBTB protein family of transcriptional repressors. ZBTB7A binds to targeted DNA via …

Exploring Emerging Therapeutic Targets and Opportunities in Neuroendocrine Tumors: Updates on Receptor Tyrosine Kinases

L Toffoli, A Ditsiou, T Gagliano - Receptors, 2024 - mdpi.com
Neuroendocrine tumors (NETs) represent a diverse group of neoplasms originating from
neuroendocrine cells, presenting varied clinical behaviors and posing significant challenges …

Identification of human papillomavirus and Rb/E2F pathway genomic alterations in mixed adeno-neuroendocrine carcinoma

F Ling, Z Yang - Indian Journal of Pathology and Microbiology, 2024 - journals.lww.com
Objective: To investigate the molecular characteristics of Rb/E2F in mixed adeno-
neuroendocrine carcinoma (MANEC). Materials and Methods: The clinicopathological …