Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2): a systemic infection
A Synowiec, A Szczepański… - Clinical microbiology …, 2021 - Am Soc Microbiol
To date, seven identified coronaviruses (CoVs) have been found to infect humans; of these,
three highly pathogenic variants have emerged in the 21st century. The newest member of …
three highly pathogenic variants have emerged in the 21st century. The newest member of …
Endothelium infection and dysregulation by SARS-CoV-2: evidence and caveats in COVID-19
The ongoing pandemic of coronavirus disease 2019 (COVID-19) caused by the acute
respiratory syndrome-coronavirus-2 (SARS-CoV-2) poses a persistent threat to global public …
respiratory syndrome-coronavirus-2 (SARS-CoV-2) poses a persistent threat to global public …
SARS-CoV-2 infection of primary human lung epithelium for COVID-19 modeling and drug discovery
Summary Coronavirus disease 2019 (COVID-19) is the latest respiratory pandemic caused
by severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2). Although …
by severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2). Although …
Targeting transcriptional regulation of SARS-CoV-2 entry factors ACE2 and TMPRSS2
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus responsible for
COVID-19, employs two key host proteins to gain entry and replicate within cells …
COVID-19, employs two key host proteins to gain entry and replicate within cells …
SARS-CoV-2 impairs interferon production via NSP2-induced repression of mRNA translation
Viruses evade the innate immune response by suppressing the production or activity of
cytokines such as type I interferons (IFNs). Here we report the discovery of a mechanism by …
cytokines such as type I interferons (IFNs). Here we report the discovery of a mechanism by …
[HTML][HTML] Systematic analysis of SARS-CoV-2 infection of an ACE2-negative human airway cell
M Puray-Chavez, KM LaPak, TP Schrank, JL Elliott… - Cell Reports, 2021 - cell.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) variants govern
transmissibility, responsiveness to vaccination, and disease severity. In a screen for new …
transmissibility, responsiveness to vaccination, and disease severity. In a screen for new …
Replication and single-cycle delivery of SARS-CoV-2 replicons
Molecular virology tools are critical for basic studies of the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) and for developing new therapeutics. Experimental …
syndrome coronavirus 2 (SARS-CoV-2) and for developing new therapeutics. Experimental …
Antiviral molecular targets of essential oils against SARS-CoV-2: A systematic review
Essential oils are potential therapeutics for coronavirus disease 2019 (COVID-19), in which
some of the volatile compounds of essential oils have been well known for their broad …
some of the volatile compounds of essential oils have been well known for their broad …
[HTML][HTML] Discovery of lead natural products for developing pan-SARS-CoV-2 therapeutics
J Pérez-Vargas, T Shapira, AD Olmstead, I Villanueva… - Antiviral research, 2023 - Elsevier
The COVID-19 pandemic, caused by severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), remains a global public health crisis. The reduced efficacy of therapeutic …
(SARS-CoV-2), remains a global public health crisis. The reduced efficacy of therapeutic …
SARS-CoV-2 infection alters mitochondrial and cytoskeletal function in human respiratory epithelial cells mediated by expression of spike protein
BH Yeung-Luk, GA Narayanan, B Ghosh, A Wally… - Mbio, 2023 - Am Soc Microbiol
ABSTRACT Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2, SCV2), which has resulted in higher morbidity and …
syndrome coronavirus 2 (SARS-CoV-2, SCV2), which has resulted in higher morbidity and …