The pathobiology of vascular dementia

C Iadecola - Neuron, 2013 - cell.com
Vascular cognitive impairment defines alterations in cognition, ranging from subtle deficits to
full-blown dementia, attributable to cerebrovascular causes. Often coexisting with …

From “truly naïve” to “exhausted senescent” T cells: when markers predict functionality

A Larbi, T Fulop - Cytometry Part A, 2014 - Wiley Online Library
The study of T cell biology has been accelerated by substantial progress at the technological
level, particularly through the continuing advancement of flow cytometry. The conventional …

Physical activity and telomere biology: exploring the link with aging‐related disease prevention

AT Ludlow, SM Roth - Journal of aging research, 2011 - Wiley Online Library
Physical activity is associated with reduced risk of several age‐related diseases as well as
with increased longevity in both rodents and humans. Though these associations are well …

Cellular senescence in cardiovascular diseases: potential age-related mechanisms and implications for treatment

F Olivieri, R Recchioni, F Marcheselli… - Current …, 2013 - ingentaconnect.com
The aging process is associated with a loss of complexity in the dynamics of physiological
systems that reduce the ability to adapt to stress, causing frailty and/or age-related diseases …

Angiogenic T-cells and putative endothelial progenitor cells in hypertension-related cerebral small vessel disease

RPW Rouhl, AECS Mertens, RJ van Oostenbrugge… - Stroke, 2012 - Am Heart Assoc
Background and Purpose—Cerebral small vessel disease (CSVD) may be caused by
endothelial dysfunction, whereas endothelial progenitor cells (EPC) may attenuate …

Lower resting and exercise-induced circulating angiogenic progenitors and angiogenic T cells in older men

MD Ross, EM Malone, R Simpson… - American Journal …, 2018 - journals.physiology.org
Aging is associated with a dysfunctional endothelial phenotype as well as reduced
angiogenic capabilities. Exercise exerts beneficial effects on the cardiovascular system …

The association of sarcopenia, telomere length, and mortality: data from the NHANES 1999–2002

PL Rippberger, RT Emeny, TA Mackenzie… - European journal of …, 2018 - nature.com
Background/objectives Sarcopenia is defined as the loss of muscle mass or function with
aging and is associated with adverse outcomes. Telomere shortening is associated with …

Developmentally determined reduction in CD31 during gestation is associated with CD8+ T cell effector differentiation in preterm infants

KM Scheible, J Emo, H Yang, J Holden-Wiltse… - Clinical …, 2015 - Elsevier
Homeostatic T cell proliferation is more robust during human fetal development. In order to
understand the relative effect of normal fetal homeostasis and perinatal exposures on CD8+ …

Effects of acute and chronic endurance exercise on intracellular nitric oxide and superoxide in circulating CD34+ and CD34 cells

NT Jenkins, RQ Landers, SJ Prior… - Journal of Applied …, 2011 - journals.physiology.org
We investigated the influence of acute and chronic endurance exercise on levels of
intracellular nitric oxide (NO), superoxide (O2·−), and expression of genes regulating the …

Circulating angiogenic cell response to sprint interval and continuous exercise

L O'Carroll, B Wardrop, RP Murphy, MD Ross… - European Journal of …, 2019 - Springer
Introduction Although commonly understood as immune cells, certain T lymphocyte and
monocyte subsets have angiogenic potential, contributing to blood vessel growth and repair …